Results 31 to 40 of about 2,519,444 (296)
Economic Principle Analysis of High-speed Railway Station Setting [PDF]
E3S Web of ConferencesChina’s construction of high-speed rail has accomplished outstanding achievements that have drawn attention from around the world and have played a significant role in driving economic and social development.
Guo Litian +3 more
doaj +1 more source
International Journal of Public Health, 2023 Objectives: The aim of this study was to explore the mechanism between public services and residents’ health, focusing on the role of spatial geographical factors.Methods: Leveraging a comprehensive panel dataset encompassing 30 mainland Chinese ...
Wei Jia, Lei Liu, Zhihao Wang, Gang Peng
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Optimisation of multiplier-less FIR filter design techniques [PDF]
This thesis is concerned with the design of multiplier-less (ML) finite impulse response (FIR) digital filters. The use of multiplier-less digital filters results in simplified filtering structures, better throughput rates and higher speed.
Cemes, Radovan
core +7 more sources
Research and designing of the catcher for the electro-vacuum frequency multiplier of the sub-millimetre range of waves [PDF]
Радиофизика и электроника, 2019 Subject and purpose. Presently, there is a problem of creation of simple in exploitation generators for a sub-millimeter range, especially in his shot-wave part.
M.V. Mil’cho
doaj +1 more source
The electoral fiscal multiplier
, 2022 The paper argues that in electoral times, a competent and opportunistic government switches from wasteful spending (e.g. pork-barrel) to non-wasteful spending.
Carmignani, Fabrizio
core +1 more source
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
SPILLOVER SPASIAL NEGATIF PERTUMBUHAN EKONOMI ANTAR KABUPATEN/KOTA DI PROVINSI JAWA TIMUR
Tataloka, 2018 Various studies have been conducted to conceive the factors of regional economic growth and its nature in order to obtain the right formulation of regional development policy.
Hani Laksono +2 more
doaj +1 more source