Results 121 to 130 of about 2,551,132 (297)

Visual hemispatial neglect, re-assessed [PDF]

open access: yes, 2008
Increased computer use in clinical settings offers an opportunity to develop new neuropsychological tests that exploit the control computers have over stimulus dimensions and timing.
List, Alexandra   +9 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Commission to Eliminate Child Abuse and Neglect Fatalities [website]

open access: yes, 2016
This website describes the history and activities of the Commission to Eliminate Child Abuse and Neglect Fatalities, established in 2012 by legislative mandate. It includes documentation and a final report that addresses the Commission's recommendations
United States. Commission to Eliminate Child Abuse and Neglect Fatalities.
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

SPATIAL NEGLECT: AN OVERVIEW OF ASSESSMENT, REHABILITATION METHODS, AND CHALLENGES ENCOUNTERED IN CLINICAL PRACTICE

open access: yesTurkish Medical Student Journal
Spatial neglect is a syndrome that stems from damage to brain regions that are critical for spatial attention and most commonly occurs post-stroke. Spatial neglect causes a lack of awareness of the contralesional space, affecting sensory perception ...
Nazife İncilay Tirsioğlu   +3 more
doaj   +1 more source

Unilateral spatial neglect

open access: yesHigher Brain Function Research, 2008
半側空間無視は,右半球損傷に伴いやすく,損傷大脳半球と反対側の刺激を無視する症状である。臨床症状の特徴は,顔や視線が健側を向いている,患側にいる人に気づかない,患側の食事の食べ残しで気づくことが多い。また読字・書字障害や談話障害などもみられる。半側空間無視の検査にはBehavioural Inattention Test やCatherine Bergego Scale などがある。発現機序には,注意障害説,方向性運動低下説,表象障害説などがある。また左視野の刺激もプライミング刺激が認められ,ある程度まで脳内で処理されている。責任病巣は,中大脳動脈,後大脳動脈,前大脳動脈領域,視床などがある。リハビリテーションは,左側へ注意をうながす訓練や代償を用いた訓練などが報告されている。その要点は ...
openaire   +2 more sources

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Understanding child neglect [PDF]

open access: yes, 2014
Child neglect is one of the most common forms of maltreatment. Neglect is a topic that encompasses complex issues, many of which are also emerging research areas. This paper aims to provide a broad overview of these issues in relation to current thinking
Debbie Scott
core  

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