Results 81 to 90 of about 3,385,835 (300)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Investigating STEM Career Interests: How Can Spatial Orientation, Mental Rotation, and Spatial Visualization Explain Them?

JTAM (Jurnal Teori dan Aplikasi Matematika)
Spatial ability plays a crucial role in shaping students' interest and career paths in STEM (Science, Technology, Engineering, and Mathematics). This quantitative study involved 60 science students aged 15–17 in Bandung, Indonesia, utilizing a spatial ...
Andari Saputra, Nanang Priatna, Jarnawi Afgani Dahlan, Niakmatul Husni   +3 more
doaj   +1 more source

Micropattern orientation and spatial localization

Vision Research, 2001
A current, popular, theory of spatial localization holds that the visual system represents the location of simple objects by a single positional tag, the accuracy of which is largely independent of the internal properties of the object. We have already presented evidence of the limitations of such a view (Keeble & Hess (1998).
Keeble, David R.T., Nishida, S.
openaire   +3 more sources

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Development of a spatial skills test for 4th grade primary school students: validity and reliability study

Frontiers in Psychology
Although several instruments have been developed to assess spatial skills, most were designed for older students, emphasize specific components of spatial ability, or have not been specifically designed to reflect the developmental characteristics and ...
Elif Aydın-Çolak, Neslihan Şahin, Mustafa Kasım Kıroğlu   +2 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Reward sharpens orientation coding independently on attention [PDF]

, 2009
Rewarding improves performance. Is it due to modulations of the output modules of the neural systems or are there mechanisms favoring more 'generous' inputs?
Stefano Baldassi, Claudio Simoncini
core  

Spatial exploration patterns determine navigation efficiency: trade-off between memory demands and distance travelled

, 2007
A total of 41 participants explored a novel square-shaped environment containing five identical boxes each hiding a visually distinct object. After an initial free exploration the participants were required to locate the objects first in a predetermined ...
Redhead, Edward S., Makany, Tamas, Dror, Itiel E.   +2 more
core   +1 more source

Spatial Orientation Test

, 2023
This project houses all relevant files to run the Spatial Orientation Test. The recommended version to use for research purposes is the JAVA format. This version is compatible with Windows 10. Explicit permission to use this task is NOT needed; however,
Alinda Friedman, Hegarty Lab, Alexander Paul Boone   +2 more
core   +2 more sources