Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Framing Social Inclusion as a Benchmark for Cycling-Inclusive Transport Policy in Kisumu, Kenya
Cycling in many cities of the Global South faces unending exclusion from street spaces despite the on-going transport policy reforms. This exclusion worsens the marginalisation of the poor majority who use this mode.
Walter Alando, Joachim Scheiner
doaj +1 more source
The influence of land use and mobility policy on travel behavior : a comparative case study of Flanders and the Netherlands [PDF]
Numerous transportation studies have indicated that the local built environment can have an important effect on travel behavior; people living in suburban neighborhoods travel more by car than people living in urban neighborhoods. In this paper, however,
De Vos, Jonas
core +4 more sources
Spatial planning and geodesign
Geodesign is a new buzzword currently used to refer to a novel but growingly popular approach to spatial planning and design. It entails the integrated use of methods and enabling technologies to address the complexity of current urban and territorial development challenges by integrated processes, including project conceptualization, knowledge ...
openaire +1 more source
Network Localization of Fatigue in Multiple Sclerosis
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo +12 more
wiley +1 more source
The professional book ,, Space planning "processed chapters on: space, concept and definition of space, space as a system, spatial economics, economic essence of space, space planning, social determinants of spatial planning, spatial planning as a process, factors development and elements in spatial planning, methodology, components and content of ...
Dimitrov, Nikola, Koteski, Cane
openaire +1 more source
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai +28 more
wiley +1 more source
The role of non-governmental actors in the spatial development of flood risks in Flanders (Belgium): towards a co-evolutionary approach in flood risk management [PDF]
Proceedings of the IV World Planning Schools Congress, July 3-8th, 2016 : Global crisis, planning and challenges to spatial justice in the north and in the southRecent challenges in flood risk management, call for the diversification of measures and the ...
Tempels, Barbara
core
Refractory Status Epilepticus Treated With Bilateral Pulvinar Deep Brain Stimulation—A Case Study
ABSTRACT New‐onset refractory status epilepticus (NORSE) arises without an identifiable cause or prior epilepsy history, with a 16%–27% mortality rate and significant long‐term neurological sequelae. Neuromodulation such as deep brain stimulation (DBS) targeting the anterior and centromedian thalamic nuclei has shown promise when the traditional ...
Mengxuan Tang +16 more
wiley +1 more source
Post-Apartheid National Spatial Development Planning in South Africa - A Brief History [PDF]
Since coming to power in 1994 successive ANC-governments have engaged in a series of attempts at national spatial development planning in South Africa. These engagements have received scant treatment in the planning literature.
Oranje, Mark
core +1 more source

