Results 41 to 50 of about 4,738,986 (282)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatial Resolution Enhancement of Brillouin Optical Correlation-Domain Reflectometry Using Convolutional Neural Network: Proof of Concept

open access: yesIEEE Access, 2021
Brillouin optical correlation-domain reflectometry (BOCDR) is a fiber-optic distributed sensing technique with single-end accessibility and high spatial resolution. In BOCDR, the measured Brillouin gain spectrum (BGS) distribution is generally given by a
Jelah N. Caceres   +5 more
doaj   +1 more source

Enhancing spatial resolution of remotely sensed data for mapping freshwater environments [PDF]

open access: yes, 2011
Freshwater environments are important for ecosystem services and biodiversity. These environments are subject to many natural and anthropogenic changes, which influence their quality; therefore, regular monitoring is required for their effective ...
Ashraf, Muhammad Salman
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Spatially Patterned Electrical Stimulation to Enhance Resolution of Retinal Prostheses [PDF]

open access: yesThe Journal of Neuroscience, 2014
Retinal prostheses electrically stimulate neurons to produce artificial vision in people blinded by photoreceptor degenerative diseases. The limited spatial resolution of current devices results in indiscriminate stimulation of interleaved cells of different types, precluding veridical reproduction of natural activity patterns in the retinal output ...
Jepson, Lauren H.   +6 more
openaire   +5 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multi-resolution, multi-sensor image fusion: general fusion framework [PDF]

open access: yes, 2011
Multi-resolution image fusion also known as pansharpening aims to include spatial information from a high resolution image, e.g. panchromatic or Synthetic Aperture Radar (SAR) image, into a low resolution image, e.g.
Palubinskas, Gintautas   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Resolution enhancement of pump-probe microscopy with an inverse-annular spatial filter

open access: yesAIP Advances, 2016
We have introduced a pupil filter, an inverse-annular pupil filter in a pump-probe photothermal microscope, which provides resolution enhancement in three dimensions.
T. Kobayashi   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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