Results 61 to 70 of about 3,119,517 (283)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Explore the theoretical basis and implementation strategy of low-carbon Urban Community Planning

open access: yesFrontiers in Environmental Science, 2022
Cities carry out various human production and living activities, consume a lot of carbon energy, become the main source of greenhouse gas emissions, and have an increasing impact on the climate.
Yan Yu
doaj   +1 more source

Spatial structure of quark Cooper pairs in a color superconductor [PDF]

open access: yes, 1999
Spatial structure of Cooper pairs with quantum numbers color 3^*, I=J=L=S=0 in ud 2 flavor quark matter is studied by solving the gap equation and calculating the coherence length in full momentum range without the weak coupling approximation.
B. C. Barrois   +37 more
core   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Spatial structure of an incompressible Quantum Hall strip

open access: yes, 1999
The incompressible Quantum Hall strip is sensitive to charging of localized states in the cyclotron gap. We study the effect of localized states by a density functional approach and find electron density and the strip width as a function of the density ...
Chklovskii   +9 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Jewish 'ghetto': formation and spatial structure [PDF]

open access: yes, 2001
Research into patterns of immigrant settlement has consistently indicated that certain areas of cities are prone to settlement by immigrant groups. This paper proposes that immigrant settlement of such areas may have a particular spacial pattern.
Penn, A, Vaughan, L
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The shapes of land lots within metropolitan space. The Łódź case

open access: yesSpace, Society, Economy, 2017
This study focuses on the spatial diversity of the shapes of land lots in metropolitan conditions viewed through the example of Łódź. The researchers placed particular attention on the diversity and compact of lot shapes.
Jerzy Dzieciuchowicz   +1 more
doaj   +1 more source

A Latent Parameter Node-Centric Model for Spatial Networks [PDF]

open access: yes, 2012
Spatial networks, in which nodes and edges are embedded in space, play a vital role in the study of complex systems. For example, many social networks attach geo-location information to each user, allowing the study of not only topological interactions ...
Larusso, Nicholas D.   +2 more
core   +3 more sources

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