The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Jewish 'ghetto': formation and spatial structure [PDF]
Research into patterns of immigrant settlement has consistently indicated that certain areas of cities are prone to settlement by immigrant groups. This paper proposes that immigrant settlement of such areas may have a particular spacial pattern.
Penn, A, Vaughan, L
core
Spatial organization and evolutional period of the epidemic model using cellular automata
We investigate epidemic models with spatial structure based on the cellular automata method. The construction of the cellular automata is from the study by Weimar and Boon about the reaction-diffusion equations [Phys. Rev. E 49, 1749 (1994)]. Our results
J. D. Murray +5 more
core +1 more source
Dispersion or Concentration for the 1.5 Generation?: Destination Choices of the Children of Immigrants in the U.S. [PDF]
This paper examines determinants of destination choice for foreign-born and 1.5 generation adult children of immigrants in the U.S. An immigrant concentration- weighted accessibility parameter is included to assess the spatial structure of destination ...
Goodwin-White, Jamie
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Equilibrium macroscopic structure revisited from spatial constraint
In classical systems, we reexamine how macroscopic structures in equilibrium state connect with spatial con- straint on the systems: e.g., volume and density as the constraint for liquids in rigid box, and crystal lattice as the constraint for ...
Yuge, Koretaka
core +1 more source
On Small Beams with Large Topological Charge II: Photons, Electrons and Gravitational Waves [PDF]
Beams of light with a large topological charge significantly change their spatial structure when they are focused strongly. Physically, it can be explained by an emerging electromagnetic field component in the direction of propagation, which is neglected
Krenn, Mario, Zeilinger, Anton
core +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Ontological Dependence, Spatial Location, and Part Structure [PDF]
This paper discusses attributively limited concrete objects such as disturbances (holes, folds, scratches etc), tropes, and attitudinal objects, which lack the sort of spatial location or part structures expected of them as concrete objects.
Moltmann, Friederike
core
Spatial structure of an individual Mn acceptor in GaAs [PDF]
The wave function of a hole bound to an individual Mn acceptor in GaAs is spatially mapped by scanning tunneling microscopy at room temperature and an anisotropic, cross-like shape is observed. The spatial structure is compared with that from an envelope-
A. Baldereschi +19 more
core +4 more sources

