Results 161 to 170 of about 576,877 (314)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Spatial variation of asthma rates in Los Angeles County by environmental and socioeconomic indicators. [PDF]

Environ Health
Khawari P, Bartell SM, Odegaard A, Vieira VM.   +3 more
europepmc   +1 more source

The reality of spatial variations of morbidity and mortality.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975
Attention is drawn to the inadequacy of using only variations of incidence rates by area as an analytical method in geographical pathology. Problems are illustrated from recent South African literature. Since widely different sizes of population-at-risk produce incidence rates that are not of comparable reliability, advances in probability mapping can ...
openaire   +3 more sources

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Spatial variation and distribution of anaemia among children aged 6-59 months in Madagascar: a population-based cross-sectional study. [PDF]

BMJ Open
Lakew G, Gemmechu MM, Tiruneh TM, Atalay YA, Yirsaw AN, Bogale EK, Gebeyehu NA, Tekoye TS, Getahun GK, Seid K, Goshu AT, Lorato SS, Desalegn M, Gelaw KA, Ashebir YG, Getahun OK.   +15 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Spatial variation and determinants of hepatitis B birth dose vaccination in Nigeria: a population-based study. [PDF]

BMC Public Health
Ogundele OA, Ogunwemimo HS, Fehintola FO, Ogundele T, Olubodun T, Olorunsola A, Fagbemi AT, Akinmoju OM, Okorosobo E.   +8 more
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Incidence and spatial variation of Parkinson's disease in the Netherlands (2017-2022): a population-based study. [PDF]

Lancet Reg Health Eur
Simões M, Peters S, Huss A, Darweesh SKL, Bloem BR, Vermeulen R.   +5 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source