Results 31 to 40 of about 5,941,547 (266)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Spatiotemporal Variations Characteristics of Precipitation in the Ailao Mountain Area during 2000 -2020 based on Geographical Weighted Regression Downscaling Method

open access: yesGaoyuan qixiang
High-quality precipitation is an important precondition to conduct the study of ecohydrology and climate change in mountain area.However, complicated terrain and scarce and uneven ground observation stations make the understanding of spatiotemporal ...
Hong WANG   +4 more
doaj   +1 more source

A Study on Spatiotemporal Changes of Ecological Vulnerability in Yunnan Province Based on Interpretation of Remote Sensing Images

open access: yesDiversity, 2023
The inherent ecological environment of mountainous regions is highly fragile, and the degree of sustainable development is low. There has not yet been a multi-phase ecological vulnerability evaluation (EVE) study based on remote sensing (RS) and GIS for ...
Zisheng Yang   +3 more
doaj   +1 more source

Spatiotemporal analysis of Indian megacities [PDF]

open access: yes, 2008
Urbanization is arguably the most dramatic form of highly irreversible land transformation. While urbanization is a worldwide phenomenon, it is exceptionally dynamic in India, where unprecedented urban growth rates have occurred over the last 30 years ...
Taubenböck, Hannes   +5 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Land use change and its impact on ecosystem service value in Xinjiang

open access: yesEnvironmental Research Communications
Xinjiang is an important hub connecting China and Eurasia and has a vital strategic position in economy, energy, and ecological security. However, owing to the fragile ecological environment in Xinjiang, substantial challenges exist in coordinating the ...
Yifeng Hao   +3 more
doaj   +1 more source

Spatiotemporal change of carbon emission efficiency in the YRB.

open access: yes, 2022
Spatiotemporal change of carbon emission efficiency in the YRB.
Zhen Yu (203197)   +2 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Spatiotemporal variation in precipitation during rainy season in Beibu Gulf, South China, from 1961 to 2016 [PDF]

open access: yes, 2020
The spatiotemporal variation in precipitation is an important part of water cycle change, which is directly associatedwith the atmospheric environment and climate change.
Yang, Hong   +5 more
core   +1 more source

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