Results 211 to 220 of about 1,087,010 (389)

Spatiotemporal Graph Neural Network Modelling Perfusion MRI [PDF]

arXiv
Perfusion MRI (pMRI) offers valuable insights into tumor vascularity and promises to predict tumor genotypes, thus benefiting prognosis for glioma patients, yet effective models tailored to 4D pMRI are still lacking. This study presents the first attempt to model 4D pMRI using a GNN-based spatiotemporal model PerfGAT, integrating spatial information ...
arxiv  

Targeting the Adenosine‐Mediated Metabolic Immune Checkpoint with Engineered Probiotic for Enhanced Chemo‐Immunotherapy

Advanced Science, Volume 12, Issue 15, April 17, 2025.
This study presents engineered probiotics that convert immunosuppressive adenosine into inosine in tumors, alleviating immunosuppression and enhancing antitumor immunity. Demonstrating efficacy in murine ectopic and orthotopic tumor models, this approach offers a promising probiotic‐based cancer immunotherapy strategy, highlighting the potential of ...
Jinhui Wang, Jing Wang, Zhijie Yu, Hongyu Wen, Chensi Zhao, Jiayong Zhong, Chuanle Xiao, Yingqiu Li, Jianqiao Xu, Jinquan Wang, Zong‐Wan Mao, Wei Xia   +11 more
wiley   +1 more source

MEA‐seqX: High‐Resolution Profiling of Large‐Scale Electrophysiological and Transcriptional Network Dynamics

Advanced Science, EarlyView.
How can we fully understand brain function and disease without uncovering the causal coordination between molecular and neural activity across space and time? MEA‐seqX tackles this challenge by integrating advanced electrophysiology, spatial transcriptomics, and artificial intelligence predictions, revealing multiscale dynamics.
Brett Addison Emery, Xin Hu, Diana Klütsch, Shahrukh Khanzada, Ludvig Larsson, Ionut Dumitru, Jonas Frisén, Joakim Lundeberg, Gerd Kempermann, Hayder Amin   +9 more
wiley   +1 more source

Optogenetically Activatable MLKL as a Standalone Functional Module for Necroptosis and Therapeutic Applications in Antitumoral Immunity

Advanced Science, Volume 12, Issue 13, April 3, 2025.
Necroptosis, a key driver of disease progression, holds promise for activating antitumor immunity. The optogenetically controlled necroptosis system, optoMLKL, bypasses upstream signaling, forming functional hotspots in membranes without RIPK3 phosphorylation.
Da‐Hye Jeong, Seokhwi Kim, Han‐Hee Park, Kyoung‐Jin Woo, Jae‐Il Choi, Minji Choi, Jisoo Shin, So Hyun Park, Myung‐Wook Seon, Dakeun Lee, Jong‐Ho Cha, You‐Sun Kim   +11 more
wiley   +1 more source

Photoacoustic Imaging in Inflammatory Orthopedic Diseases: Progress toward Precise Diagnostics and Predictive Regulation

Advanced Science, Volume 12, Issue 14, April 10, 2025.
With the intensification of aging issues, inflammatory orthopedic diseases almost occurs in every elderly people, which are becoming increasingly severe. Persistent inflammation of joints often leads to irreversible tissue damage and loss of organ function, while early diagnosis and timely intervention are crucial for reducing the personal and social ...
Mengyi Huang, Haoyu Yu, Rongyao Gao, Yuxin Liu, Xuhui Zhou, Limin Fu, Jing Zhou, Luoyuan Li   +7 more
wiley   +1 more source

Cubic Phase‐Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA

Advanced Science, Volume 12, Issue 17, May 8, 2025.
In this study, a chemically engineered zwitterionic phospholipids derived from 1,2‐dioleoyl‐3‐sn‐glycero‐phosphoethanolamine (DOPE), DOPE‐Cx, are designed. The DOPE‐Cx lipids induce a cubic phase upon mixing with phosphatidylcholine, facilitate membrane fusion‐mediated endosomal escape, and enhance the functional delivery of mRNA.
Kazuki Iwakawa, Rikako Sato, Mariko Konaka, Yuma Yamada, Hideyoshi Harashima, Yusuke Sato   +5 more
wiley   +1 more source

Structural Colors Go Active

Advanced Science, Volume 12, Issue 12, March 27, 2025.
This review explores the principles and recent advances in dynamic structural colors, including SPR, LSPR, FP, and Mie resonances. It highlights key tuning strategies involving functional materials and external stimuli, evaluating their performance and limitations.
Xinting Li, Jiancun Zhao, Junyi Yang, Yihui Huo, Yiting Yu   +4 more
wiley   +1 more source

Spatiotemporal fusion for spectral remote sensing: A statistical analysis and review

Journal of King Saud University: Computer and Information Sciences, 2023
Guangsheng Chen, Hailiang Lu, Weitao Zou, Linhui Li, Mahmoud Emam, Xuebin Chen, Weipeng Jing, Jian Wang, Chao Li   +8 more
semanticscholar   +1 more source

FREQ‐NESS Reveals the Dynamic Reconfiguration of Frequency‐Resolved Brain Networks During Auditory Stimulation

Advanced Science, EarlyView.
A new analytical pipeline, FREQuency‐resolved Network Estimation via Source Separation (FREQ‐NESS), reveals how the brain at rest is organized in frequency‐specific networks and dynamically rearranges during auditory stimulation. By analyzing source‐reconstructed magnetoencephalography (MEG) data, FREQ‐NESS uncovers the networks' prominence, spatial ...
Mattia Rosso, Gemma Fernández‐Rubio, Peter Erik Keller, Elvira Brattico, Peter Vuust, Morten L Kringelbach, Leonardo Bonetti   +6 more
wiley   +1 more source

STAFNet: an adaptive multi-feature learning network via spatiotemporal fusion for EEG-based emotion recognition. [PDF]

Front Neurosci
Hu F, He K, Qian M, Liu X, Qiao Z, Zhang L, Xiong J.   +6 more
europepmc   +1 more source