Results 251 to 260 of about 1,087,010 (389)

A Synthetic Facultative CAM‐Like Shuttle in C3 Rice Plants

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
This study utilizes gene editing and multigene stacking to design a facultative CAM‐like metabolic pathway that includes a stomatal regulation module, a carboxylation module, a decarboxylation module, and a malate transport module. A facultative CAM‐like metabolic pathway is created in C₃ rice, achieving compatibility between the C₃ cycle and the CAM ...
Suting Wu   +12 more
wiley   +1 more source

Smart Organic–Inorganic Copolymer Nanoparticles Distinguish Between Microglia and Cancer Cells for Synergistic Immunotherapy in Glioma

open access: yesAdvanced Science, EarlyView.
The tumor microenvironment‐responsive nanoagonists are developed using an organic–inorganic copolymer composed of the polymer (PC6AB) and manganous phosphate ionic oligomers (MnP). PC6AB with membranolytic activity selectively interacts with tumor cell membranes to induce immunogenic cell death, while MnP activates the STING pathway in immune cells ...
Shiming Zhang   +14 more
wiley   +1 more source

Molecular Engineering Strategies for Organic Pre‐Sodiation: Progress and Challenges

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
This review delves into the molecular engineering strategies for organic pre‐sodiation techniques, examining the intricate structure‐activity relationships between functional group modifications and oxidation decomposition/reduction potentials of organic pre‐sodiation materials.
Zhijian Cai, Huai Chen, Fujun Niu
wiley   +1 more source

From Multi‐Omics to Visualization and Beyond: Bridging Micro and Macro Insights in CAR‐T Cell Therapy

open access: yesAdvanced Science, EarlyView.
This review explores how multi‐omics, visualization technologies, and AI drive CAR‐T therapy from the micro to the macro level, from preclinical studies to clinical applications. The convergence of these approaches provides deeper insight into CAR‐T cell mechanisms, aids in structural optimization, and significantly enhances treatment efficacy and ...
Yuting Gong   +4 more
wiley   +1 more source

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