Results 61 to 70 of about 1,146,451 (358)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
, 2018 Discussion of atomistic and monistic theses about abstract ...
Cowling, Sam, Trogdon, Kelly
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Pedestrian Trajectory Prediction with Structured Memory Hierarchies
, 2018 This paper presents a novel framework for human trajectory prediction based on multimodal data (video and radar). Motivated by recent neuroscience discoveries, we propose incorporating a structured memory component in the human trajectory prediction ...
A Roy +10 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Memory-Augmented Temporal Dynamic Learning for Action Recognition
, 2019 Human actions captured in video sequences contain two crucial factors for action recognition, i.e., visual appearance and motion dynamics. To model these two aspects, Convolutional and Recurrent Neural Networks (CNNs and RNNs) are adopted in most ...
Wang, Dong, Wang, Qi, Yuan, Yuan
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Dynamic gesture recognition based on feature fusion network and variant ConvLSTM
IET Image Processing, 2020 Gesture is a natural form of human communication, and it is of great significance in human–computer interaction. In the dynamic gesture recognition method based on deep learning, the key is to obtain comprehensive gesture feature information.
Yuqing Peng +4 more
doaj +1 more source
Nonlinear wave-wave interactions in quantum plasmas
, 2010 Wave-wave interaction in plasmas is a topic of important research since the 16th century. The formation of Langmuir solitons through the coupling of high-frequency (hf) Langmuir and low-frequency (lf) ion-acoustic waves, is one of the most interesting ...
Misra, A. P., Shukla, P. K.
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source