Results 31 to 40 of about 2,631,204 (260)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Prediction of Metro Station Foundation Pit Excavation Deformation Based on ConvLSTM Model

Chengshi guidao jiaotong yanjiu
ObjectiveDeformation prediction in foundation pit engineering is of great significance for ensuring the construction safety. Traditional prediction methods have limitations in handling the complex spatiotemporal evolution characteristics of foundation ...
Di WU, Jianjun SUN, Rangxian LU
doaj   +1 more source

Modeling and manipulating spacetime objects in a true 4D model

Journal of Spatial Information Science, 2017
The concept of spacetime has long been used in physics to refer to models that integrate 3D space and time as a single 4D continuum. We argue in this paper that it is also advantageous to use this concept in a practical geographic context by realizing a ...
Ken Arroyo Ohori, Hugo Ledoux, Jantien Stoter   +2 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

SpeQNet: Query-Enhanced Spectral Graph Filtering for Spatiotemporal Forecasting

Applied Sciences
Accurate spatiotemporal forecasting underpins high-stakes decision making in smart urban systems, from traffic control and energy scheduling to environment monitoring.
Zongyao Feng, Konstantin Markov
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

The Evolution of Modeling Approaches: From Statistical Models to Deep Learning for Locust and Grasshopper Forecasting

Insects
Locust outbreaks cause a significant threat to global food security and ecosystem stability, with particularly severe consequences in grassland regions, where grasshoppers also exert considerable ecological pressure.
Wei Sui, Jing Wang, Dan Miao, Yijie Jiang, Guojun Liu, Shujian Yang, Wei You, Zhi Li, Xiaojing Wu, Hu Meng   +9 more
doaj   +1 more source

Semantic Modeling in Materials Science and Engineering With Platform MaterialDigital Core Ontology 3.0

Advanced Engineering Materials, EarlyView.
The community‐driven Platform MaterialDigital Core Ontology (PMDco) 3.0 is introduced as a Basic Formal Ontology‐aligned semantic backbone for the processing–structure–properties paradigm in Materials Science and Engineering. Modular engineering, automated releases, and validation workflows are highlighted and key semantic patterns for materials ...
Markus Schilling, Philipp von Hartrott, Jörg Waitelonis, Thomas Hanke, Henk Birkholz, Hossein Beygi Nasrabadi, Khashayar Razghandi, Kamilla Zaripova, Felix Thonagel, Fabian Neuhaus, Martin Glauer, Lars Vogt, Harald Sack, Lutz Mädler, Bernd Bayerlein, Chris Eberl   +15 more
wiley   +1 more source

A Deep Multimodal Fusion Framework for Noncontact Temperature Detection in Ceramic Roller Kilns

Applied Sciences
Accurate temperature control in ceramic roller kilns is critical for ensuring product quality; however, it remains challenging due to nonlinear thermal dynamics and the spatial lag inherent in traditional contact-based sensors. To address the limitations
Kuiyang Cai, Shanchuan Tu, Shujuan Wang
doaj   +1 more source

DNA‐Templated 2D Heterostructures as Phototriggered Dynamic Nanohybrids: From Releasing Molecular Loads to Controlling Enzyme Biocatalytic Function

Advanced Functional Materials, EarlyView.
DNA strands are employed both as dynamic linkers and nanoscale templates for the integration of Ag2S nanoparticles on MoS2, which in turn imparted photothermal responsiveness; this feature permits the selective cargo (fluorophore, quantum dots or an enzyme) release from the MoS2 surface in response to local heat induced by light irradiation.
Kai Chen, Haosen Miao, Weiying Hong, Matteo Palma   +3 more
wiley   +1 more source