Results 101 to 110 of about 6,417,207 (338)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Accent Conversion via Formant-based Spectral Mapping and Pitch Contour Modification [PDF]

open access: yes, 2011
A thesis submitted in partial fulfilment of requirements of the University of Wolverhampton for the degree of Master of PhilosophyAccent conversion intends to change the accent of a speaker to a desired accent and preserve the speaker’s voice identity ...
Zheng, Dang Cong, Dang Cong Zheng
core   +2 more sources

Visual Speaker Identification Using Lip and Body Movements [PDF]

open access: yes, 2013
Speaker identification has been studied in many fields such as image processing, audio processing, artificial intelligence and speech recognition. Two of these areas are integrated together in order to identify the speaker.
Muhammad Usman Ghani Khan; University of Engineering & Technology, Lahore   +4 more
core  

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

Speaker Identification Using Modular Recurrent Neural Networks

open access: yes, 1995
This paper demonstrates a speaker identification system based on recurrent neural networks trained with the Real-time Recurrent Learning algorithm (RTRL). A series of speaker identification experiments based on isolated digits has been conducted.
N.W. Mak, M.W. Mak
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Multibiometric security in wireless communication systems [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 05/08/2010.This thesis has aimed to explore an application of Multibiometrics to secured wireless communications.
Sepasian, Mojtaba
core   +4 more sources

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

AN AUDITORY-BASED SPEAKER IDENTIFICATION SYSTEM IN ACOUSTIC NOISES

open access: yesДоклады Белорусского государственного университета информатики и радиоэлектроники, 2019
The speaker recognition system in acoustic noises with the use of anthropomorphic speech signal processing is considered. A transform based on the cochlear model and its applications for speaker recognition are described in details.
D. N. Kruchok, A. A. Petrovsky
doaj  

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