Results 61 to 70 of about 1,724,683 (286)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Phoneme and sub-phoneme T-normalization for text-dependent speaker recognition [PDF]
, 2008 Proceedings of Odyssey 2008: The Speaker and Language Recognition Workshop, Stellenbosch, South AfricaTest normalization (T-Norm) is a score normalization technique that is regularly and successfully applied in the context of text-independent speaker ...
González Rodríguez, Joaquín +2 more
core +1 more source
On the combination of speech and speaker recognition
8th European Conference on Speech Communication and Technology (Eurospeech 2003), 2003 This paper investigates an approach that maximizes the joint posterior probabil ity of the pronounced word and the speaker identity given the observed data. This probability can be expressed as a product of the posterior probability of the pronounced word estimated through an artificial neural network (ANN), and the likelihood of the data estimated ...
BenZeghiba, Mohamed Faouzi +1 more
openaire +3 more sources
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Speaker Recognition in Uncontrolled Environment: A Review
Journal of Intelligent Systems, 2013 Speaker recognition has been an active research area for many years. Methods to represent and quantify information embedded in speech signal are termed as features of the signal.
Karamangala Narendra +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
EURASIP Journal on Advances in Signal Processing, 2021 Text-independent speaker recognition is widely used in identity recognition that has a wide spectrum of applications, such as criminal investigation, payment certification, and interest-based customer services. In order to improve the recognition ability
Qinghua Zhong +4 more
doaj +1 more source
An Introduction to Speech and Speaker Recognition
Computer, 1990 Five approaches that can be used to control and simplify the speech recognition task are examined. They entail the use of isolated words, speaker-dependent systems, limited vocabulary size, a tightly constrained grammar, and quiet and controlled environmental conditions. The five components of a speech recognition system are described: a speech capture
Richard D. Peacocke, Daryl H. Graf
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source