Results 31 to 40 of about 452,247 (265)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
RELATION OF DEAF PERSONS TOWARDS BILINGUALISM AS COMMUNICATION MODE
Human Research in Rehabilitation, 2013 Bilingualism of a deaf child implies concurrent cognition and usage of sign language, as community language and oral-voice language as language of greater community in which deaf persons live.
Naim Salkić
doaj +2 more sources
PERCEPTION OF PARENTAL SUPPORT BY DEAF AND HARD-OF-HEARING STUDENTS
Human Research in Rehabilitation, 2019 The aim of the paper was to determine the perception of parental support and understanding by deaf and hard-of-hearing students. The sample consisted of 47 deaf and hard-of-hearing students, both genders, with an average age of 16 ± 1.27 years ...
Meliha Povlakić Hadžiefendić +2 more
doaj +1 more source
The Geoengineering Dilemma: To Speak or not to Speak [PDF]
Climatic Change, 2006 An intriguing dichotomy has developed within the field of atmospheric and climate research. On the one side, it has become common practice to examine pessimistic future scenarios of anthropogenic pollutant emissions and their environmental impacts. Not surprisingly, compared to the alternative “best guess” or “maximum feasible reduction” emissions ...
openaire +2 more sources
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Speaking with Frankenstein [PDF]
Journal of Medical Humanities, 2020 This collaborative essay experimentally applies the insights of Mary Shelley's 1818 gothic fantasy Frankenstein to clinical interactions between present-day physicians and the patients they, akin to Shelley's human protagonist, so often seem to bring (back) to life.
Jayne Lewis, Johanna Shapiro
openaire +4 more sources
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Visegrad Group and its Presence in the Mashriq Region
Politics in Central Europe, 2019 This paper provides an outline about Hungary’s, Poland’s, Slovakia’s and Czechia’s relationships to the Mashriq region, especially Jordan, Israel and Egypt.
Döring Franziska
doaj +1 more source