Results 111 to 120 of about 19,665 (266)

The relationship between cortical synaptic terminal density marker SV2A and glutamate early in the course of schizophrenia: a multimodal PET and MRS imaging study

Translational Psychiatry
Loss of glutamatergic terminals is hypothesised to contribute to excitation-inhibition imbalance in schizophrenia, supported by evidence that the normal positive association between glutamate concentrations and synaptic terminal density is not found in ...
Ellis Chika Onwordi, Thomas Whitehurst, Ekaterina Shatalina, Richard Carr, Ayla Mansur, Atheeshaan Arumuham, Martin Osugo, Tiago Reis Marques, Sameer Jauhar, Susham Gupta, Sofia Pappa, Ravi Mehrotra, Maja Ranger, Nikola Rahaman, Eugenii A. Rabiner, Roger N. Gunn, Sridhar Natesan, Oliver D. Howes   +17 more
doaj   +1 more source

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta, Luigi Angelo Fiorito, Roberta Vescovo, Anna Virgilio, Giulia Amato, Giuseppe Cimino   +5 more
wiley   +1 more source

Carga alostática y condiciones de trabajo y de salud Allostatic load and working and health conditions

Revista Cubana de Salud y Trabajo
Introducción: El Índice de Carga Alostática provee un marco potencial para evaluar el efecto de los factores del ambiente físico y psicosocial de trabajo en la salud del trabajador a través de indicadores de deterioro temprano, evaluados durante la ...
Alberto Fabián Villavicencio Bencomo, Georgina Maritza López Pumar, Maritza Aguilar León, Roselia Inés Bustamante Rojas   +3 more
doaj  

Contrasting roles of school and public libraries in lower primary pupils' reading

British Educational Research Journal, EarlyView.
Abstract Libraries represent an important institutional component of children's reading socialisation, yet their role is often treated as uniform despite substantial differences between school and public libraries. This study examines how visits to school and public libraries relate to pupils' reading attitudes, practices and self‐assessed reading ...
Kateřina Balcarová, Jiří Balcar
wiley   +1 more source

Quantitative Analysis Reveals Hitchhiking Drives Polysorbate Hydrolase Persistence Via Host Cell Protein–Antibody Interactions

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Polysorbate‐degrading host cell proteins (HCPs) represent a critical challenge in the manufacturing of monoclonal antibody therapeutics due to their potential to persist during downstream processing. While their enzymatic activity has been characterized, the role of direct HCP‐mAb interactions, particularly those involving polysorbate ...
Melanie Maier, Lukas Griesinger, Matthias Franzreb, Simon Kluters   +3 more
wiley   +1 more source

Beyond medical prescription: Unveiling coping strategies' role between perceived quality of care and treatment adherence among hypertensive patients.

PLOS Global Public Health
Beyond medical prescription for hypertension treatment, management requires consistent level of adherence, high quality of care and adaptive coping strategies, which are rarely considered.
Prince Owusu Adoma, Francis Aacquah, Christopher Bawiah, Samuel Oke, Abubakari Yakubu   +4 more
doaj   +1 more source

Zero Deforestation Commitments and Industry 4.0 Enabling Technologies: An Analysis of Their Role in Mitigating Deforestation

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines the role of corporate zero‐deforestation commitments (ZDCs) and Industry 4.0 (I4.0) enabling technologies in mitigating deforestation. Drawing on data from 110 companies included in the Forest 500 dataset, the research explores whether sustainability commitments and digital innovation influence firms' deforestation ...
Valentina Beretta, Eugenia Parodi, Celine Buschmann   +2 more
wiley   +1 more source

Environmental Disclosure Under Mandatory Regulation in EU Listed Companies: An Institutional Analysis

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines corporate environmental reporting practices among listed companies in the European Union during the period 2018–2022, within the context of the Non‐Financial Reporting Directive (NFRD). To this end, an Environmental Disclosure Index (EDI) is constructed based on qualitative reporting items, and panel‐data models are ...
Rosalva Pinto‐Braga, Pedro Lorca Fernández, Javier de Andrés Suárez   +2 more
wiley   +1 more source

Exploring the relationship between ankle strength and endurance factors and the severity and level of ischemia in patients with peripheral arterial disease

Journal of Cardiothoracic Surgery
Background Peripheral Arterial Disease (PAD) is a global health concern, particularly among aging populations. While previous studies have examined various aspects of PAD, the role of ankle muscle strength and endurance in assessing ischemia severity ...
Mohammad Hassani, Mohammad Hassabi, Shaghayegh Khodabakhshian, Mohammad Javanbakht, Shiva Aliabbar, Alireza Movahedi, Helia Ghorbani, Mahdi Mohebbi, Hamidreza Movahedi, Mohamad Hosein Tabatabaei Nodoushan, Abolfazl Mirani   +10 more
doaj   +1 more source

Towards a Developmental Retribution and Reciprocity Model (RRM): Implications for Youth Justice

Behavioral Sciences &the Law, EarlyView.
ABSTRACT Youth justice systems are frequently justified by reference to developmental change, yet chronological age is often treated as a proxy for underlying psychological processes. This paper develops a Developmental Retribution and Reciprocity Model (RRM), integrating evolutionary criminology with contemporary developmental neuroscience to clarify ...
Evelyn Svingen
wiley   +1 more source