Results 31 to 40 of about 3,858,494 (262)

The Patient Experience of Integrated Care Scale: A Validation Study among Patients with Chronic Conditions Seen in Primary Care

International Journal of Integrated Care, 2018
Introduction: Valid and comprehensive instruments to measure integrated care are required to capture patient experience and improve quality of patient care.
Heithem Joober, Maud-Christine Chouinard, Jenny King, Mireille Lambert, Émilie Hudon, Catherine Hudon   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Spearman’s rank correlation coefficient between environmental and biological variables.

, 2016
Spearman’s rank correlation coefficient between environmental and biological variables.
Shaoqing Wang (501204), Haibo Li (629817), Zhiqiang Xu (103072), Wuchang Zhang (2601856), Tian Xiao (2601859), Guangtao Zhang (1267662)   +5 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Full‐reference tone‐mapped images quality assessment

IET Image Processing, 2021
Various tone mapping operators have been proposed to convert the high dynamic range images to low dynamic ranges to improve visualization on low dynamic range displays.
Mohammad Reza Faraji
doaj   +1 more source

A comprehensive analysis of the correlation between maximal clique size and centrality metrics for complex network graphs

Egyptian Informatics Journal, 2021
We seek to identify one or more computationally light-weight centrality metrics that have a high correlation with that of the maximal clique size (the maximum size of the clique a node is part of) - a computationally hard measure.
Natarajan Meghanathan
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Spearman’s rank-order correlation.

, 2018
Spearman’s rank-order correlation.
Takashi Sato (140116), Yoshio Koga (5742668), Koichi Kobayashi (2423707), Osamu Tanifuji (4971799), Hiroshi Koga (2268859), Naoto Endo (325630), Satoshi Watanabe (103008), Hiroshi Yamagiwa (5742674), Toshihide Fujii (5742671), Tomoharu Mochizuki (4971790), Ryota Katsumi (5184701), Go Omori (5742677)   +11 more
core   +1 more source

Study 2 Spearman’s rank correlation coefficients.

, 2022
Study 2 Spearman’s rank correlation coefficients.
Francesca Malandrone (9658997), Federica Carfì (14210046), Sara Carletto (439273), Silvia Bianchi (587492), Fulvio Ricceri (300193), Richard J. Davidson (7046501), Pelin Kesebir (485105), Alberto Catalano (12792249), Francesco Oliva (19111), Luca Ostacoli (439274), Claudio Gentili (234570)   +10 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source