Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Child and Family Welfare in Sweden [PDF]
, 2002 Sweden has no special Children’s Act because regulations on children are included in the Social Services Act from 1980, supplemented by an act regulating compulsory care.
Andersson, Gunvor
core +1 more source
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
A szociális és szolidáris gazdaság csírái a magyarországi vidéki térségekben (Seeds of Social and Solidarity Economy in Hungarian Rural Areas) [PDF]
DETUROPE, 2014 The social and solidarity economy (SSE) is an emerging sector of the European economies. It’s importance is demonstrated by millions of employees and significant share of GDP.
Éva Fekete
doaj
Legal, Political and Practical Obstacles to the Enforcement of Labor Laws in Panama [PDF]
, 2004 The report describes past and present labor laws and reforms in Panama as they pertain to basic labor rights. Beluche offers a discussion on the legal, political, and practical obstacles that prevent compliance to labor ...
Beluche, Olmedo
core +1 more source
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Universal service obligations in utility concession contracts and the needs of the poor in Argentina's privatization [PDF]
The authors summarize the main lessons emerging from Argentina's experience, including universal service obligations in concession contracts. They discuss free-riding risks, moral hazard problems, and other issues that arise when social concerns are ...
Chisari, Omar, Estache, Antonio
core
Use of resources in special schools = Y defnydd o adnoddau mewn ysgolion arbennig [PDF]
, 2010 While special schools generally make good use of available funds, many councils’ funding and support arrangements do not reflect the changed context in which schools ...
Body, Gillian
core
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
Community case study: Community-driven strategies to build a socially inclusive rural county
Frontiers in Public HealthMitchell County, Kansas is a rural county with a strong sense of local identity and a population committed to community well-being. Like many rural areas, however, residents experience structural challenges to social connection, including geographic ...
Elizabeth Ablah +6 more
doaj +1 more source