Results 61 to 70 of about 171,041,152 (259)

ORGANIZATIONAL AND METHODICAL FEATURES OF THE ACTIVITY OF STUDENT SCIENTIFIC SOCIETIES, ORIENTED TO PERSONAL SELF-DEVELOPMENT OF YOUTH

Вестник Тамбовского университета. Серия: Гуманитарные науки, 2018
The research is aimed at identifying organizational and methodological approaches to the organization of social and cultural activities, oriented to the student’s self-development.
E. I. Pankova
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Fall 2021: Struggles Bring Opportunity

, 2021
In the Fall 2021 issue of Advances in Social Work, we are pleased to present 16 full-length papers written by 30 authors from different regions of the U.S. including Puerto Rico as well as from Ghana. An underlying theme of many of these contributions is
Adamek, Margaret E.
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Values Education in Higher Education

Medisur, 2011
Present times are characterized by dramatic changes in different areas of life. Twenty-first century professionals need a special training that enables them to venture into various branches of knowledge. Therefore, they must have an original thinking and
Miriam Iglesias León, Manuel Cortés Cortés, Norma Mur Villar, Coralia Perez Maya, María José Aguilar Cordero   +4 more
doaj   +2 more sources

2012 Agenda: The 24th National Symposium on Doctoral Research in Social Work

, 2012
The Ohio State University College of Social ...
Ohio State University. College of Social Work
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Vol. 29 No. 2 (2023): A Call for Social Work Educators to Confront and Dismantle Systemic Racism WITHIN Social Work Programs (Issue 1)

, 2023
Full version of Vol. 29 No. 2 (2023): A Call for Social Work Educators to Confront and Dismantle Systemic Racism WITHIN Social Work Programs (Issue ...
School of Social Work
core