Results 301 to 310 of about 4,834,128 (418)

Disintegration of the KITENIN/ErbB4 Functional Complex by the Flavonoid Hispidulin Suppresses Colorectal Cancer Progression

open access: yesAdvanced Therapeutics, EarlyView.
Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı   +7 more
wiley   +1 more source

Analytical Description of Nanowires: Morphing Wurtzite Structure Cross Sections to Match Arbitrary Convex Shapes

open access: yesAdvanced Theory and Simulations, EarlyView.
Analytic morphing of wurtzite nanowire cross sections to arbitrary shapes yields numbers of nanowire atoms, of bonds between these and of nanowire interface bonds, plus the nanowire cross section area. The ratios of above variables help to interpret any spectroscopic nanowire data which depend on diameter and cross section shape, and can be applied to ...
Dirk König, Sean C. Smith
wiley   +1 more source

Accurate and Efficient Behavioral Modeling of GaN HEMTs Using An Optimized Light Gradient Boosting Machine

open access: yesAdvanced Theory and Simulations, EarlyView.
Machine Learning (ML) and optimization have permeated almost every aspect of engineering applications. Recent years have seen great traction toward ML‐based GaN HEMT modelling. However, ML‐based GaN HEMT models are mostly developed using variants of Artificial Neural Network (ANN).
Saddam Husain   +2 more
wiley   +1 more source

Immune Checkpoint PD‐L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK

open access: yesAdvanced Science, EarlyView.
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou   +7 more
wiley   +1 more source

Altered Brain‐Behavior Association During Resting State is a Potential Psychosis Risk Marker

open access: yesAdvanced Science, EarlyView.
The study detects a potential multimodal biomarker that can be promising for identifying early markers of psychosis. It shows a consistent brain‐behavior association between a circuit of interconnected regions and executive function in neurotypical controls and individuals at various stages of psychosis.
Leonardo Fazio   +22 more
wiley   +1 more source

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