Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan+16 more
wiley +1 more source
The Use of Video-Based Learning to Elucidate the Biological Mechanisms Linking Oral Health With Specific Systemic Medical Conditions. [PDF]
Leira Y+6 more
europepmc +1 more source
De Novo Reconstruction of 3D Human Facial Images from DNA Sequence
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao+11 more
wiley +1 more source
The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He+6 more
wiley +1 more source
Health in Kerala: exploring achievements and remaining challenges of health systems reform using an equity lens. [PDF]
D HS+3 more
europepmc +1 more source
The poor electronic conductivity and intrinsic Jahn–Teller distortion in NASICON‐type Na4VMn(PO4)3(NVMP) led to insufficient capacity delivery and sluggish Na+ diffusion. Herein, a multiscale integration strategy is proposed to construct a unique 3D nanorod cathode enriched with V/O defects by utilizing DMF as a solvent.
Jingwen Zhao+7 more
wiley +1 more source
Structural factors shaping health-seeking behaviour among breast cancer survivors in the Gaza Strip: A qualitative study utilising the right to health framework. [PDF]
Ammar-Shehada W+3 more
europepmc +1 more source
Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi+10 more
wiley +1 more source
Optimal Discharge Education: Evidence for Enhancing Family Preparedness for Premature Infants. [PDF]
Zhang L, He J, Zhou Y, Li X.
europepmc +1 more source