Results 331 to 340 of about 4,834,128 (418)

Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration

open access: yesAdvanced Science, EarlyView.
The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan   +16 more
wiley   +1 more source

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

open access: yesAdvanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao   +11 more
wiley   +1 more source

Dimethyl Itaconate Alleviates Escherichia coli‐Induced Endometritis Through the Guanosine‐CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae

open access: yesAdvanced Science, EarlyView.
The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He   +6 more
wiley   +1 more source

Accelerating Electrochemical Responses of Na4VMn(PO4)3 via Bulk‐Defects and Architecture Engineering for High‐Performance Sodium‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
The poor electronic conductivity and intrinsic Jahn–Teller distortion in NASICON‐type Na4VMn(PO4)3(NVMP) led to insufficient capacity delivery and sluggish Na+ diffusion. Herein, a multiscale integration strategy is proposed to construct a unique 3D nanorod cathode enriched with V/O defects by utilizing DMF as a solvent.
Jingwen Zhao   +7 more
wiley   +1 more source

Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity

open access: yesAdvanced Science, EarlyView.
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi   +10 more
wiley   +1 more source

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