Results 91 to 100 of about 1,630,196 (296)
Проблеми трибологіїThis article examines ways to improve the wear resistance of agricultural machinery components operating under intense abrasive wear conditions. The study focused on cultivator shanks made of 50, 50KhGA, and 65G structural steels. The aim of the study is
D.D. Marchenko, K.S. Matvyeyeva
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Assessment Report 2014 KTC Limited, China AA0000000364 [PDF]
, 2014 This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Development a technique for semi-quantitative risk assessment of exposure to chemicals
Salāmat-i kār-i Īrān, 2020 Background and Aim: Employee exposure assessment through long-term monitoring is not feasible due to the complexity of sampling and analysis methods in all operating conditions.
Davood Eskandari +3 more
doaj
Classroom assistants in primary schools: Employment and deployment
, 2002 The study investigates the ways in which classroom assistants in primary schools are deployed in classrooms, and the terms and conditions under which they are employed.
Cable, Carrie +4 more
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NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Positive practice positive outcomes: a handbook for professionals in the criminal justice system working with offenders with learning disabilities (2011 ed.) [PDF]
, 2011 Updated version of the handbook by the same name published by CSIP in 2007. "This handbook is intended as an introduction to working with offenders with learning disabilities. This group includes police suspects and defendants in court.
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source