Results 71 to 80 of about 4,974,002 (279)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
THE RATIONAL CHARACTER TABLE OF SPECIAL LINEAR GROUPS [PDF]
Journal of Sciences, Islamic Republic of Iran, 1998 In this paper we will give the character table of the irreducible rational representations of G=SL (2, q) where q= , p prime, n>O, by using the character table and the Schur indices of SL(2,q).
doaj
A finiteness condition on the coefficients of the probabilistic zeta function [PDF]
International Journal of Group Theory, 2013 We discuss whether finiteness properties of a profinite group $G$ can be deduced from the coefficients of the probabilisticzeta function $P_G(s)$. In particular we prove that if $P_G(s)$ is rational and all but finitely many non abelian composition ...
Hoang Dung Duong, Andrea Lucchini
doaj
Mass Media and Special Interest Groups [PDF]
Media revenues are an important determinant of media behavior. News coverage depends not only on the preferences of media consumers but also on the preferences of advertisers or subsidizing groups.
Maria Petrova
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
State of health and roads of his improving at children of school age in special medical groups. [PDF]
Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2010 Tendencies of an aggravation of symptoms of health of children are construed. It is exhibited magnifications of variety and a degree of gravity of diseases.
Sidorchenko E. N.
doaj
Challenges and perspectives of tobacco cessation in special groups of patients and populations. [PDF]
Breathe (Sheff), 2023 Tsikrika S +4 more
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source