Results 171 to 180 of about 18,001,535 (330)

Communicating for the Safe Use of Medicines: Progress and Directions for the 2020s Promoted by the Special Interest Group of the International Society of Pharmacovigilance. [PDF]

Drug Saf, 2023
Bahri P, Bowring G, Edwards BD, Anton C, Aronson JK, Caro-Rojas A, Hugman BPJ, Mol PG, Trifirò G, Ilic K, Daghfous R, Fermont I, Furlan G, Gaissmaier W, Geer MI, Hartigan-Go KY, Houÿez F, Neth H, Norgela G, Oppamayun Y, Raynor DKT, Bouhlel M, Santoro F, Sultana J.   +23 more
europepmc   +1 more source

Special Interest Group

Role of participants - All partnersRather than create yet another network for social entrepreneurs and innovators, we will capitalise on the networks of all consortium partners. However, in particular, we will utilise the already existing open platform of the ISPIM and its Special Interest Groups (SIGs), which use digital technologies as well as face ...
openaire   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

P114: Over-representation of PMS2CL pseudogene interference in PMS2 testing in a non-European cohort

Genetics in Medicine Open
Emily Maxwell, Ayanna Boyce, Caitlin Reid, Ashley Marsh, Kevin Beezhold, Timothy Komala, Katie Lang, Marcy Richardson, Colby Chase   +8 more
doaj   +1 more source

ACMG Medical Directors' Special Interest Group survey: Current challenges for medical genetics clinics. [PDF]

Genet Med Open
Dulchavsky M, Keegan CE, Robin NH, Haldeman-Englert C, Dhar SU, Hisama FM.   +5 more
europepmc   +1 more source

The International Society of Pharmacovigilance Vaccines Special Interest Group: Challenges and Opportunities. [PDF]

Drug Saf, 2022
Chandler RE.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Complications of Botulinum Toxin, Fillers, and Threads: A Narrative Review by the Special Interest Group (SIG) Aesthetics, Indian Association of Dermatologists, Venereologists and Leprologists (IADVL) Academy. [PDF]

Cureus
Kandhari R, Sharma R, Aggarwal I, Arora G, Ranka N.   +4 more
europepmc   +1 more source

Implementation of Artificial Intelligence-Assisted Endoscopy Across Canada-The CAG Artificial Intelligence Special Interest Group. [PDF]

J Can Assoc Gastroenterol, 2023
von Renteln D, Byrne MF, Wong C, Menard C, Donnellan F, Barkun A.   +5 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source