Results 121 to 130 of about 5,732,689 (284)
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
[The meaning of specialization for the nurse in the field of stomas].
Revista latino-americana de enfermagem, 2004 This study aimed at knowing and understanding the meanings and perceptions of the enterostomal therapist (ET) about this specialty, using the methodological framework of Social Representation Theory. Three major Units were identified: the ET as a professional, the ET and the client, the ET as a person from an analysis of 12 ET's discourse.
Maria Angela, de Paula +1 more
openaire +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
The Meaning of Rotation in the Special Theory of Relativity [PDF]
Proceedings of the National Academy of Sciences, 1922 openaire +2 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
RUDN Journal of Informatization in Education, 2008 Modern realities dictate a need of introduction ICT for teaching and educational process that entails necessity of forming of ICT-COMPETENCE of teachers, which is their professional characteristic, a component of their pedagogical skill.
N J Kulikova
doaj
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
On the meanings of subsetting, specialization and redefinition in UML
, 2011 UML 2 has improved the expressiveness of the language with respect to associations in several manners. A significant one has been the introduction of the association redefinition concept. Association subsetting and association specialization have been included in UML since its earliest versions and share some relevant features with association ...
Costal Costa, Dolors +2 more
openaire +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source