Results 81 to 90 of about 5,732,689 (284)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A Special Property of Linear Estimates of the Normal Mean

The Annals of Statistics, 1976
Let $X$ be a normal random variable with mean $\theta$ and variance 1 and consider the problem of estimating $\theta$ with squared error loss. If $\delta(x) = ax + b$ is a linear estimate with $0 \leqq a \leqq 1$ then it is well known that $\lambda\delta$ is an admissible proper Bayes estimate for $\lambda \in (0, 1)$.
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

5. Creative Approaches in the Education of Students with Severe Multiple Disability

Review of Artistic Education, 2016
The paper presents an empirical study in the area of special education, which clarifies the function of creative techniques, their application, pupils’ preferences and implementation of creative techniques in the processes of special education ...
Kantor Jiří
doaj   +1 more source

On Sheep, Light, And Life: A Special Meaning for 2015

LASER THERAPY, 2014
Welcome to the festive season issue of your journal! By the time this issue is in your hand (or on your computer screens), we will be bidding farewell to 2014 and welcoming 2015, watching the Year of the Horse gallop off, and the Year of the Sheep (or Ram, or Goat, whichever version you prefer) amble its ovine way in. Strictly speaking, the sheep makes
openaire   +3 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

INFLUENCE OF SPECIAL TRAINING MEANS ON THE COMPETITIVE RESULT OF WEIGHTLIFTERS

Физическая культура. Спорт. Туризм. Двигательная рекреация
Objectives: The article shows that the results of high-skilled weightlifters in special preparation exercises of high intensity have a high and statistically significant relationship with the competitive result.
Большой Александр Владимирович
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Degrees of the approximations by some special matrix means of conjugate Fourier series

Demonstratio Mathematica, 2019
In this paper we will present the pointwise and normwise estimations of the deviations considered by W. Łenski, B. Szal, [Acta Comment. Univ. Tartu. Math., 2009, 13, 11-24] and S. Saini, U. Singh, [Boll. Unione Mat. Ital., 2016, 9, 495-504] under general
Kranz Radosława, Rzepka Aleksandra, Sylwestrzak-Maślanka Ewa   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source