Results 21 to 30 of about 166,923,470 (217)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Regular matrix methods of summability and real interpolation [PDF]
, 2021 We show that the Banach–Saks property with respect to a regular positive matrix method of summability is inherited by the real interpolation spaces from a space forming the interpolation family and possessing this property. The proof refers to the Galvin–
Kurlej, Konrad, Kryczka, Andrzej
core +2 more sources
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Isospectral deformations of Eguchi-Hanson spaces a case study in noncompact noncommutative geometry [PDF]
, 2008 We study the isospectral deformations of the Eguchi-Hanson spaces along a torus isometric action in the noncompact noncommutative geometry. We concentrate on locality, smoothness and summability conditions of the nonunital spectral triples, and relate ...
Yang, Chen
core
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Stečkin inequalities for summability methods
, 1997 Stečkin proved an inequality on Fejér means of Fourier series He said, Proving similar inequality for other summability method is an interesting problem.
Jia-Ding Cao
core +1 more source
, 2022 In this paper, weighted mean methods of summability are given in intuitionistic fuzzy normed spaces IF NS. Also, some Tauberian conditions are defined for the weighted mean methods of summability in IF NS. © 2022, University of Mazandaran.
Yapali, Reha, Polat, Harun
core +1 more source