Results 131 to 140 of about 767 (209)

Metrnl: A Novel Therapeutic Target in Atherosclerosis

iNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

Interdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang, Kai Wang, Liangbo Wang, Wencong Li, Hao Guo, Meng Xu, Tinghao Wang, Jiahui Ren, Ting Zhu, Jiahui Wang, Wenxing Cui, Jinpeng Zhou, Yang Tian, Liying Han, Chengxuan Guo, Shuoyao Ma, Qiang Wang, Zhihong Li, Yaning Cai, Jingyu Dong, Xun Wu, Haixiao Liu, Yan Qu   +22 more
wiley   +1 more source

HYGIENIC EVALUATION OF THE BACTERIAL CONTAMINATION OF A MULTIDISCIPLINARY HOSPITAL IN DONBASS IN MODERN CONDITIONS. PART II. DYNAMICS DURING THE WAR YEARS

Медицина в Кузбассе
A comparative hygienic assessment of bacterial contamination of air, washes, sterility of materials, skin of the operating field and surgeons' hands in the units of a multidisciplinary hospital in different time periods of the war period.
Вячеслав Александрович Бондаревский-Колотий, Дмитрий Олегович Ластков, Анна Григорьевна Сихарулидзе   +2 more
doaj  

Financial Development Under Economic Sanctions: Short‐Run Market Responses and Long‐Run Institutional Adjustment

International Studies of Economics, EarlyView.
ABSTRACT This paper examines how the financial development of the target economy evolves under the long‐lasting economic sanctions, emphasizing the temporal patterns of the impact. Using panel data for 136 economies from 1980 to 2021 and an event‐study approach, we identified a temporal pattern that illustrates how economic sanctions exert a ...
Yu Jiang, Xue Meng
wiley   +1 more source

Labor Market Institutions, Fiscal Multipliers, and Macroeconomic Volatility

Journal of Applied Econometrics, EarlyView.
ABSTRACT How do labor market institutions shape the transmission of government spending shocks and macroeconomic volatility? We develop a theoretical model in which labor market institutions affect fiscal transmission through their effect on wage rigidity, job separation, and matching frictions.
Maximilian Boeck, Jesús Crespo Cuaresma, Christian Glocker   +2 more
wiley   +1 more source

Monuments to Injustice and the Ethics of Dark Tourism: A Research Note

Journal of Applied Philosophy, EarlyView.
ABSTRACT This research note aims to motivate philosophical examination of the ethical tensions surrounding ‘dark tourism’ and monuments to injustice. While such monuments function to acknowledge past wrongs, educate the public, and serve reparative functions, their presentation as tourist destinations can undermine these purposes.
Kok‐Chor Tan
wiley   +1 more source

Dignity's Dilemma: Categorical Objections to Autonomous Weapons and Their Pacifist Entailments

Journal of Applied Philosophy, EarlyView.
ABSTRACT Dignity objections to autonomous weapon systems are prominent in contemporary military ethics, yet their theoretical foundations remain underexamined. This article reconstructs those foundations, showing what categorical dignity objections require to function as absolute prohibitions.
Timothy Dubber
wiley   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

From Empire to Aid: Analysing Persistence of Colonial Legacies in Foreign Aid to Africa

Journal of International Development, EarlyView.
ABSTRACT For decades now, Western development agencies and donors have been castigated for their colonial biases in providing aid to Africa. It is well established that donors provide considerably more foreign aid to their former colonies relative to other countries.
Swetha Ramachandran
wiley   +1 more source

You, Me, and the AI: The Role of Third‐Party Human Teammates for Trust Formation Toward AI Teammates

Journal of Organizational Behavior, EarlyView.
ABSTRACT As artificial intelligence (AI) becomes increasingly integrated in teams, understanding the factors that drive trust formation between human and AI teammates becomes crucial. Yet, the emergent literature has overlooked the impact of third parties on human‐AI teaming.
Türkü Erengin, Roman Briker, Simon B. de Jong   +2 more
wiley   +1 more source