Results 1 to 10 of about 12,317,814 (294)

A Novel Nomogram for Predicting Warfarin-Related Bleeding: A Retrospective Cohort Study

Clinical and Applied Thrombosis/Hemostasis
Warfarin is a widely used anticoagulant, and bleeding complications are the main reason why patients discontinue the drug. Currently, there is no nomogram model for warfarin-associated bleeding risk. The aim of this study was to develop a risk-prediction
Shaohua Yang MD, Wensen Yao MD
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Decoding autoimmune disease with single-cell immune repertoire and transcriptome sequencing: mechanisms and therapeutic opportunities

Frontiers in Immunology
Autoimmune diseases result from a breakdown of immune tolerance, driving the aberrant activation and clonal expansion of self-reactive T and B cells. Progress has been limited by the inability to link clonal identity to functional states at single-cell ...
Shuqing Wang, Shuqing Wang, Zhao Dong, Zhao Dong, Yuefang Liu, Yuefang Liu, Xianhe Ren, Xianhe Ren, Xin Wang, Xin Wang, Hongsong Yu, Hongsong Yu   +11 more
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Berberine protects against hypoxia-induced intestinal injury through modulation of gut microbiota and bile acid metabolism

Frontiers in Immunology
BackgroundHigh-altitude hypoxia disrupts intestinal homeostasis by impairing the epithelial barrier, triggering inflammation, and promoting microbial translocation. Berberine (BER), a natural isoquinoline alkaloid with antimicrobial and anti-inflammatory
Hao Zhang, Hao Zhang, Hao Zhang, Penghui Ye, Penghui Ye, Penghui Ye, Wenlong Yang, Wenlong Yang, Wenlong Yang, Yuanyuan Dou, Yuanyuan Dou, Yuanyuan Dou, Zhenhao Tian, Zhenhao Tian, Zhenhao Tian, Nu Zhang, Nu Zhang, Nu Zhang, Ning Cui, Ning Cui, Ning Cui, Leming Sun, Leming Sun, Leming Sun, Zhuoyi Liu, Yijia Chen, Xiru Liu, Hui Yang, Hui Yang, Hui Yang   +29 more
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Special Treatment Everywhere, Special Treatment Nowhere

, 2015
This symposium essay disputes the conventional wisdom that “special treatment” mandates are exceptional within employment discrimination jurisprudence. To the contrary, they are endemic, and necessarily so. This is true even within disparate treatment jurisprudence. The reasons are twofold.
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Tumor treating fields in malignant pleural mesothelioma: from cytoskeletal collapse to immunophenotypic conversion

Frontiers in Immunology
The therapeutic efficacy in malignant pleural mesothelioma (MPM) is severely hindered by its dense stromal barrier and immunosuppressive microenvironment.
Xiaofeng Ma, Xiaofeng Ma, Zhuo Zuo, Yulong Sun, Hong An   +4 more
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Translating physical stress into biological signals: precision electro-oncology based on conformational changes of electro-sensitive receptors and parameterized immune remodeling

Frontiers in Oncology
Tumor Treating Fields (TTFields) and pulsed electric fields (PEF) have emerged as a fourth modality in oncological treatment, succeeding surgery, radiotherapy, and pharmacotherapy.
Wei Shi, Wei Shi, Mengya Zhao, Xiaofeng Ma, Xiaofeng Ma, Li Dong, Yulong Sun   +6 more
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When Anxiety Meets Anxiety: A Dyadic Co-Regulation Model of Teacher-Student Mathematics Anxiety in Special Education

Education Sciences
Research on mathematics anxiety (MA) transmission has examined how teacher anxiety shapes student outcomes through instructional behavior. A more complex reality remains unaddressed.
Dana Sury, Oshrat On, Einat Kleider Tesler   +2 more
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Nonlinear relationship between blood urea nitrogen to albumin ratio and in-hospital mortality in non-diabetic patients with non-ST-segment elevation myocardial infarction

Frontiers in Nutrition
BackgroundThe blood urea nitrogen (BUN) to albumin (ALB) ratio (BAR) is a novel biomarker that reflects both nutritional and inflammatory status and has been linked to the prognosis of various acute and chronic diseases.
Lixia Yuan, Wensen Yao
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Not Just a Fish Killer: Multi-Organ Toxicity and Mechanisms of 6PPD-Quinone

Toxics
6PPD-Quinone (6PPD-Q) is a tire derivative formed by the oxidation of N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD), a commonly used antioxidant and ozone stabilizer in rubber products, and has emerged as a significant environmental concern ...
Pinzhi Dong, Meijun Liu, Haiyan Wang, Jin Chen, Xiaorong Xu, Hailong Su, Ming Qin, Junmin Luo   +7 more
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Special Considerations in the Treatment of Pregnancy Rhinitis

Women's Health, 2005
Pregnancy rhinitis is a common condition that is not yet fully recognized by the public. This form of rhinitis affects approximately one in five pregnant women, can start in almost any gestational week, and disappears after delivery. However, as it reduces quality of life, and also possibly affects the fetus, treatment is often required.
openaire   +2 more sources