Results 31 to 40 of about 1,164,136 (338)

CATE Lasso: Conditional Average Treatment Effect Estimation with High-Dimensional Linear Regression [PDF]

open access: yesarXiv, 2023
In causal inference about two treatments, Conditional Average Treatment Effects (CATEs) play an important role as a quantity representing an individualized causal effect, defined as a difference between the expected outcomes of the two treatments conditioned on covariates.
arxiv  

GENERAL AND SPECIAL TREATMENT OF TUBERCULOSIS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1896
It is a source of pleasure to state in the words of an authority, Solis Cohen, that tuberculosis of the lungs is a curable disease. This authority, however, believes that the statement must be considerably modified with reference to the outcome of every case.
openaire   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Effect of Carbonation on the Leachability of Solidified/Stabilized Lead-Contaminated Expansive Soil

open access: yesAdvances in Civil Engineering, 2021
Lime, fly ash, and alkaline residue are used widely as effective binders to solidify/stabilize heavy metal-contaminated expansive soil. Carbonation, however, may influence the effectiveness of solidification/stabilization (S/S) by decomposing hydration ...
Fusheng Zha   +9 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

TM4SF1 overexpression in tumor-associated endothelial cells promotes microvascular invasion in hepatocellular carcinoma

open access: yesFrontiers in Oncology
BackgroundMicrovascular invasion (MVI) is linked to poor prognosis, early recurrence and post-surgical intrahepatic metastasis of hepatocellular carcinoma (HCC) but roles of tumor-associated endothelial cells (TECs) remain unclear. The aim of the current
Junwu Guo   +10 more
doaj   +1 more source

Occurrence of FVIII Inhibitors in Hemophilia A Patients Following an Institutional Switch to a Third Generation B-Domain-Deleted FVIII

open access: yesClinical and Applied Thrombosis/Hemostasis, 2023
In 2018, Refacto AF R , a B-domain-deleted third-generation FVIII concentrate, became our preferential product. After the introduction, the development of inhibitors was prospectively monitored; retrospectively, we sought for risk factors in the patients
Louise H Hooimeijer MD   +6 more
doaj   +1 more source

Personalized medicine: Special treatment [PDF]

open access: yesNature, 2014
Therapies targeted at the specific genetics of a patient's lung cancer have proved harder to realize than expected.
openaire   +3 more sources

Special Issue “The Prevention and Treatment of Atherosclerosis” [PDF]

open access: yesJournal of Clinical Medicine, 2022
This editorial summarizes the 10 scientific papers that contributed to the Special Issue of the Journal of Clinical Medicine: ‘The Prevention and Treatment of Atherosclerosis’ [...]
openaire   +3 more sources

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

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