Results 91 to 100 of about 120,528,310 (270)

A Recovery-Oriented Suicide Prevention Program Led by Peer Specialists for Veterans With Serious Mental Illness: Protocol for a Pilot Randomized Controlled Trial

open access: yesJMIR Research Protocols
BackgroundVeterans with serious mental illness (SMI) have significantly elevated suicide risk compared to those without SMI. This group may also experience cognitive and functional impairments that complicate suicide prevention ...
Samantha Chalker   +4 more
doaj   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

open access: yesAdvanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker   +11 more
wiley   +1 more source

Kresling Origami‐Based Metamaterial Robot for Dynamic Electromagnetic Control

open access: yesAdvanced Science, EarlyView.
A reconfigurable metamaterial system integrates deformable origami units with high‐permittivity ceramic plates. Pneumatic switching between structural states alters local resonance conditions, enabling dynamic radar stealth and adaptive microwave reflection for mobile communication.
Xinxi Zeng   +13 more
wiley   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

open access: yesAdvanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma   +10 more
wiley   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

open access: yesAdvanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl   +20 more
wiley   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

open access: yesAdvanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

The Patients’ Perspective for the Impact of Late Detection of Ocular Diseases on Quality of Life: A Cross-Sectional Study

open access: yesClinical Optometry, 2023
Ahmed Almazroa,1,2 Hessa Almatar,1,2 Reema Alduhayan,1,2 Maram Albalawi,2,3 Mansour Alghamdi,4 Saja Alhoshan,5 Suhailah Alamri,1,2 Norah Alkanhal,1,2 Yara J Alsiwat,1,2 Saad Alrabiah,6 Mohammed Aldrgham,7 Ahmed A AlSaleh,8 Hessa Abdulrahman Alsanad,9 ...
Almazroa A   +13 more
doaj  

Van der Waals Heterostructures for Next‐Generation Spintronics: Multiferroic‐Mediated Magnetoelectric Properties

open access: yesAdvanced Science, EarlyView.
As CMOS technology approaches fundamental energy limits, new paradigms for low‐power information processing are required. Magnetic systems are attractive for their spin transport, yet current‐induced magnetization control is energy inefficient. Multiferroic heterostructures enable energy‐efficient electric field manipulation of magnetism.
Donghyeon Lee   +3 more
wiley   +1 more source

Intramuscular Vitamin B12 Treatment in Transcobalamin II Deficiency: Case Series Clinical Outcomes

open access: yesThe Application of Clinical Genetics
Ali M Sawlan,1 Msaed Alotaibi,1 Rayan M Alharbi,1 Nimr A Alwahbi,1 Manar Alshammary,2 Ali Mohammad Alasmari,2 Fuad Al Mutairi3,4 1College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs (MNG ...
Sawlan AM   +6 more
doaj  

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