The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
The Feasibility of the Role of Clinical Nurse Specialist in Taiwan: The Delphi Technique
[[abstract]]本研究之目的在探討護理界及醫界對發展專科護理師角色之共識,以作爲未來國內發展專科護理師之參攷,其主要重點如下:(1)探討發展專科護理師的可行性,(2)訂立專科護理師遴選標准,(3)制定專科護理師訓練內容,(4)規劃專科護理師之角色功能範圍,(5)探討專科護理師之資格維持辦法,(6)建議專科護理師之甄審機構,(7)建議專科護理師合宜分科。本研究採德爾菲研究法(Delphi technique)。共進行三回合問卷審視後,專家間已産生共識 ...
盧美秀;林佳靜;林秋芬;廖美南;張丹蓉
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Leadership Competencies of the Medical-Surgical Nursing Specialist Nurse. [PDF]
Pires MFS +4 more
europepmc +1 more source
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu +9 more
wiley +1 more source
'It made me feel part of the team, having my homework to do' - women and specialist nurse experiences of remote follow-up after ovarian cancer treatment: a qualitative interview study. [PDF]
Kennedy F +3 more
europepmc +2 more sources
Reducing last-minute cancellations of elective urological surgery-effectiveness of specialist nurse preoperative assessment. [PDF]
Spazzapan M +7 more
europepmc +1 more source
Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma +11 more
wiley +1 more source
Identifying Structure, Process and Outcome Factors of the Clinical Specialist Nurse: A Scoping Review Study. [PDF]
Hashemi S +5 more
europepmc +1 more source
Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Specialist nurse-led cross-linking service for Keratoconus, the Leeds experience. [PDF]
Prajapati R +7 more
europepmc +1 more source

