Results 141 to 150 of about 99,252 (304)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

The Feasibility of the Role of Clinical Nurse Specialist in Taiwan: The Delphi Technique

open access: yes, 2017
[[abstract]]本研究之目的在探討護理界及醫界對發展專科護理師角色之共識,以作爲未來國內發展專科護理師之參攷,其主要重點如下:(1)探討發展專科護理師的可行性,(2)訂立專科護理師遴選標准,(3)制定專科護理師訓練內容,(4)規劃專科護理師之角色功能範圍,(5)探討專科護理師之資格維持辦法,(6)建議專科護理師之甄審機構,(7)建議專科護理師合宜分科。本研究採德爾菲研究法(Delphi technique)。共進行三回合問卷審視後,專家間已産生共識 ...
盧美秀;林佳靜;林秋芬;廖美南;張丹蓉
core  

Leadership Competencies of the Medical-Surgical Nursing Specialist Nurse. [PDF]

open access: yesRev Bras Enferm, 2023
Pires MFS   +4 more
europepmc   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

Reducing last-minute cancellations of elective urological surgery-effectiveness of specialist nurse preoperative assessment. [PDF]

open access: yesInt J Qual Health Care, 2023
Spazzapan M   +7 more
europepmc   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

open access: yesAdvanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma   +11 more
wiley   +1 more source

Identifying Structure, Process and Outcome Factors of the Clinical Specialist Nurse: A Scoping Review Study. [PDF]

open access: yesIran J Nurs Midwifery Res, 2023
Hashemi S   +5 more
europepmc   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

Specialist nurse-led cross-linking service for Keratoconus, the Leeds experience. [PDF]

open access: yesEye (Lond), 2023
Prajapati R   +7 more
europepmc   +1 more source

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