Results 171 to 180 of about 99,252 (304)

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

Advanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang, Xiandi Meng, Yanbao Xin, Kuirong Mao, Huizhu Tan, Changkai Ma, Xiuxiu Cong, Mengfei Zhao, Meiling Yu, Si Chen, Yue Hou, Yong‐Guang Yang, Tianmeng Sun   +12 more
wiley   +1 more source

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Development of an Evaluation Index System for Chinese Medicine Specialist Nurse Training Effectiveness: A Delphi-AHP Study. [PDF]

J Multidiscip Healthc
Qi Y, Li H, Mao J, Yu F, Chen Y, Zhong Y, Lu J, Gu Y, Zhang W.   +8 more
europepmc   +1 more source

Modeling the Multiple Sclerosis Specialist Nurse Workforce by Determination of Optimum Caseloads in the United Kingdom. [PDF]

Int J MS Care, 2021
Punshon G, Sopala J, Hannan G, Roberts M, Vernon K, Pearce A, Leary A.   +6 more
europepmc   +1 more source

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

Advanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen, Jiahui Xie, Yi Liao, Junyu Li, Longqi Liu, Xin Gao, Hongmin Cai   +6 more
wiley   +1 more source

How Divergent Views of Specialist Nurse Status Affect IQNs' Skill Utilisation in Australia. [PDF]

J Nurs Manag
Kurup C, Burston AS, Betihavas V, Jacob ER.   +3 more
europepmc   +1 more source

DMS‐MaPseq and DREEM Analyses Implicate the Critical Role of RNA Structural Dynamics in Turnip Yellow Mosaic Virus Pathogenicity

Advanced Science, EarlyView.
RNA structural profiling of Turnip Yellow Mosaic Virus by DMS‐MaPseq and DREEM analyses uncover that viral genome‐wide RSS is highly complicated and heterogeneous, with alternative RSSs widely distributed across the genome. Notably, the viral 3’ tRNA‐like structure adopts alternative conformations in vivo.
Jiaying Zhu, Changhao Li, Chisimbily Onyia, Xindi Li, Xingxing Yan, Songxiao Zhong, Taerin Oh, Xiuren Zhang   +7 more
wiley   +1 more source

NURS 820 Clinical Nurse Specialist

, 1992
Course syllabus for NURS 820 Clinical Nurse Specialist Course description: An examination of historical, theoretical, and conceptual bases of CNS role development, advanced practice and evaluation.
Fraser, C. M.
core  

NURS 820 Clinical Nurse Specialist

, 2001
Course syllabus for NURS 820 Clinical Nurse Specialist Course description: An examination of historical, theoretical, and conceptual bases of CNS role development, advanced practice and evaluation.
MacMullen, Nancy J.
core  

Problem based Learning: A Reflective Account of its Application in Health Professional Education

, 2011
This article is a critically reflective account discussing the practical application of Problem Based Learning (PBL) in Health Professional Education (HPE).
Covill, Carl, Burton, Rob, Kaye, Vicky, Burton, Rob L.   +3 more
core