Results 181 to 190 of about 427,855 (303)

Healthcare Professionals' Perspectives on Barriers and Facilitators in Care and Rehabilitation of Adults with Myasthenia Gravis in Neurological Departments in Denmark. [PDF]

J Multidiscip Healthc
Olesen LK, Werlauff U, Missel M, Schirakow L, Handberg C.   +4 more
europepmc   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Benchmarking large language models for medical education: performance on the clinical laboratory technician qualification examination. [PDF]

Front Med (Lausanne)
Wang Y, Jiang Y, Jin W, Lin W, Xu Y, Wang J, Wang X, Fang Z.   +7 more
europepmc   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

A Comparative Analysis of AI-Language Models' MCQ Performance versus Medical Students Across Different Pediatric Topics. [PDF]

Adv Med Educ Pract
Bolgova O, Mavrych V, Almidani E, Alshareef T, Kemahlı S.   +4 more
europepmc   +1 more source

Quantitative Mass Spectrometry‐Based Biodistribution of Monoclonal Antibodies: An Alternative to Radio‐Biodistribution

Advanced Science, EarlyView.
Monoclonal antibodies are powerful anticancer therapeutics targeting tumor‐associated antigens. Mass spectrometry enables precise and accurate quantification of mAbs in tumor plasma and healthy organs. Unlike ligand binding assay and radioactivity, mass spectrometry does not suffer from matrix effects and labelling artefacts while facilitating method ...
Domenico Ravazza, Sheila Dakhel Plaza, Samuele Cazzamalli, Andrea Ciamarone, Andrea Galbiati, Riccardo Stucchi, Frederik Peissert, Emanuele Puca, Dario Neri, Ettore Gilardoni   +9 more
wiley   +1 more source

A hierarchical analysis of predictors of perioperative competency in Chinese operating room nurses. [PDF]

Belitung Nurs J
Fu C, Abhicharttibutra K, Lertwatthanawilat W, Wichaikhum OA.   +3 more
europepmc   +1 more source

Knowledge Card: Filling LLMs' Knowledge Gaps with Plug-in Specialized Language Models

By design, large language models (LLMs) are static general-purpose models, expensive to retrain or update frequently. As they are increasingly adopted for knowledge-intensive tasks, it becomes evident that these design choices lead to failures to ...
Shi, Weijia, Balachandran, Vidhisha, Bai, Yuyang, Feng, Shangbin, He, Tianxing, Tsvetkov, Yulia   +5 more
core  

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

Effectiveness of virtual clinical simulation in palliative care education for nursing students: Protocol of a randomized controlled trial. [PDF]

PLoS One
Sun Z, Wen P, Zhang L, Zhang X, Yang X, Liu C, Fu J, Yang M.   +7 more
europepmc   +1 more source