Results 81 to 90 of about 3,332,531 (404)

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source

Congenital syphilis in a preterm newborn with gastrointestinal disorders and postnatal growth restriction

Italian Journal of Pediatrics, 2022
Background Congenital syphilis (CS) depends on the placental transmission of Treponema pallidum (TP) spirochetes from an infected mother to fetus during pregnancy. It shows a wide clinical variability with cutaneous and visceral manifestations, including
Gregorio Serra, Maurizio Carta, Maria Rita Di Pace, Eleonora La Sala, Ettore Piro, Sergio Salerno, Ingrid Anne Mandy Schierz, Alessia Vassallo, Mario Giuffrè, Giovanni Corsello   +9 more
doaj   +1 more source

Bibliometric Approximation of a Scientific Specialty by Combining Key Sources, Title Words, Authors and References [PDF]

Journal of Informetrics, 12(1), 113-132, 2018, 2017
Bibliometric methods for the analysis of highly specialized subjects are increasingly investigated and debated. Information and assessments well-focused at the specialty level can help make important decisions in research and innovation policy. This paper presents a novel method to approximate the specialty to which a given publication record belongs ...
arxiv   +1 more source

Changes in medical students' views of internal medicine careers from 1990 to 2007.

Archives of Internal Medicine, 2011
BACKGROUND The United States faces a shortage of primary care physicians and declining number of medical students choosing primary care careers. METHODS We conducted a secondary analysis of 2 similar national surveys of senior medical students from ...
M. Schwartz, S. Durning, M. Linzer, K. Hauer   +3 more
semanticscholar   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

New insights on partial trisomy 3q syndrome: de novo 3q27.1-q29 duplication in a newborn with pre and postnatal overgrowth and assisted reproductive conception

Italian Journal of Pediatrics, 2023
Background Duplications of the long arm of chromosome 3 are rare, and associated to a well-defined contiguous gene syndrome known as partial trisomy 3q syndrome. It has been first described in 1966 by Falek et al., and since then around 100 patients have
Gregorio Serra, Vincenzo Antona, Marcello Cimador, Giorgia Collodoro, Marco Guida, Ettore Piro, Ingrid Anne Mandy Schierz, Vincenzo Verde, Mario Giuffrè, Giovanni Corsello   +9 more
doaj   +1 more source

Quantification of BERT Diagnosis Generalizability Across Medical Specialties Using Semantic Dataset Distance [PDF]

arXiv, 2020
Deep learning models in healthcare may fail to generalize on data from unseen corpora. Additionally, no quantitative metric exists to tell how existing models will perform on new data. Previous studies demonstrated that NLP models of medical notes generalize variably between institutions, but ignored other levels of healthcare organization. We measured
arxiv  

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Severe clinical immunodeficiency in a patient with human immunodeficiency virus infection and relatively high CD4 counts: a case report

Journal of Medical Case Reports, 2019
Background The coexistence of neuromeningeal cryptococcosis and Kaposi’s sarcoma is not surprising in a patient with human immunodeficiency virus infection and a low CD4 count, although it is rarely described.
Mickael Essouma, Larry N. Tangie, Mazou N. Temgoua, Ulrich Gabin Kenfack, Antonin N. Ndam, Celestin Danwang   +5 more
doaj   +1 more source

Sign-Out Snapshot: Evaluation Of Written Sign-Outs Among Specialties And Role Of Hospitalist Sign-Out [PDF]

, 2013
SIGN-OUT SNAPSHOT: EVALUATION OF WRITTEN SIGN-OUTS AMONG SPECIALTIES AND ROLE OF HOSPITALIST SIGN-OUT. Amy R. Schoenfeld, Robert L. Fogerty, Mohammed Salim, and Leora I. Horwitz. Section of General Internal Medicine, Department of Internal Medicine, Yale
Schoenfeld, Amy
core   +1 more source