Results 91 to 100 of about 377,569 (313)

Defining the specialty [PDF]

open access: yesEmergency Medicine Journal, 2004
Curriculum and textbook initiatives It is now 30 years since the first consultants in accident and emergency medicine were appointed. The Faculty of Accident and Emergency Medicine celebrated its first decade in November 2003. We live in turbulent times with service pressures increasing while others outside our specialty (not fully understanding what ...
openaire   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

DEVELOPMENT OF EDUCATIONAL PROGRAMS FOR ECONOMY AND MANAGEMENT AT TECHNICAL UNIVERSITY WITH APPLICATION OF COMPETENCE-BASED APPROACH

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2015
The article analyzes the Russian system of the higher education from the state educational standards of higher education on federal state educational standards of higher education according to which educational process is guided not by the content of ...
Oxana Yu. Eremicheva   +2 more
doaj  

Classification of occupations and specialisations for the labour market – from the past to the future [PDF]

open access: yesEdukacja Ustawiczna Dorosłych, 2019
The aim of the article is to outline the relationship between the classification of occupations and specializations and other systemic tools facilitating labour market policy and education policy in particular European classification ...
Agnieszka MAJCHER-TELEON   +1 more
doaj  

Referral criteria for outpatient specialty palliative cancer care: an international consensus [PDF]

open access: bronze, 2016
David Hui   +9 more
openalex   +1 more source

ICT in the study of foreign languages by students of technical specialties

open access: diamond, 2021
Наталія Вовчаста   +5 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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