Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The Impact of the Los Angeles Healthy Kids Program on Access to Care, Use of Services, and Health Status [PDF]
Presents survey results on the impact of the Healthy Kids program, which provides uninsured children with comprehensive coverage, on access to care, unmet needs, use of specialty and dental services, health status, and parental ...
Embry Howell, Lisa Dubay, Louise Palmer
core +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Kelly R Murphy, John E McManigle, Benjamin M Wildman-Tobriner, Amy Little Jones, Travis J Dekker, Barrett A Little, Joseph P Doty, Dean C Taylor Duke Healthcare Leadership Program, Duke University School of Medicine ...
Murphy KR +7 more
doaj
Curriculum and textbook initiatives It is now 30 years since the first consultants in accident and emergency medicine were appointed. The Faculty of Accident and Emergency Medicine celebrated its first decade in November 2003. We live in turbulent times with service pressures increasing while others outside our specialty (not fully understanding what ...
openaire +2 more sources
The Group Employed Model as a Foundation for Health Care Delivery Reform [PDF]
Outlines group employed models, with salaried primary and specialty care physicians and quality of care- and satisfaction-based incentives as high-quality, low-cost alternatives to fee-for-service; elements of success; and implications beyond ...
David Helms +4 more
core
The Specialty Board Movement at the Crossroads: Reaction to the Paper by Kevin B. Weiss, MD [PDF]
Janet M. Corrigan
openalex +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
What Adds Value in Specialty Coffee? Managerial Implications from Hedonic Price Analysis of Central and South American E-Auctions [PDF]
We analyze price and quality information at the procurement level in the specialty coffee supply chain using data from small and large volume e-auctions.
Donnet, M. Laura +2 more
core +1 more source
A Snapshot of U.S. Physicians: Key Findings From the 2008 Health Tracking Physician Survey [PDF]
Analyzes survey data on U.S. physicians' compensation system, career satisfaction, acceptance of new patients, managed care contracts, and charity care provision by demographics, type of practice, specialty, geographic location, and other ...
Alwyn Cassil +2 more
core

