Results 41 to 50 of about 377,569 (313)

Outpatient Antibiotic Resistance Patterns of Escherichia coli Urinary Isolates Differ by Specialty Type

Microbiology Spectrum, 2022
Antibiotic-resistant E. coli infections represent a major cause of morbidity and mortality and pose a challenge to antibiotic stewardship. We analyzed a large outpatient data set of E.
Lauren Frisbie, Scott J. Weissman, Hema Kapoor, Marisa D’Angeli, Ann Salm, Jeff Radcliff, Peter Rabinowitz   +6 more
doaj   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

‘We are working in specialty units’—An exploratory qualitative study

Nursing Open
Aim To explore related support needs of general nurses in specialty mental health units and provide references for formulating a model to support this population working in mental health care units. Design An exploratory qualitative design.
Mphedziseni Esther Rangwaneni, Ndidzulafhi Selina Raliphaswa, Mary Maluleke, Vusiwana Patricia Letlalo, Thingahangwi Cecilia Masutha, Duppy Manyuma, Langanani Makhado, Tinyiko Nelly Rikhotso   +7 more
doaj   +1 more source

Content and efficiency of the technique, aimed at formation of "working" and "dynamic position" of lower acrobates, taking into account the requirements of the chosen specialty

Journal of Education, Health and Sport, 2020
The content of the methodology aimed at the formation of “working” and “dynamic posture” of bottom acrobats who train at the stage of preliminary basic training is discussed in the article presented.
Vladyslava Denysenko, Yuliya Maksymova, Mikhail Filippov   +2 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Decisión de estudiar medicina: Factores determinantes y elección de la especialidad Decision to Study Medicine: Determinants and Specialty Choice

Acta Médica Costarricense, 2012
Introducción: La decisión de estudiar medicina depende de múltiples factores incluyendo aspectos internos (personales) y otros externos al individuo. Conocer estos factores puede ser útil para la administración del plan de estudios de la carrera y para ...
Juan Ignacio Padilla-Cuadra, Leonel Vindas-Sánchez, Alfonso Villalobos-Pérez   +2 more
doaj