Results 61 to 70 of about 377,569 (313)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Department «Metallurgy of ferrous and non-ferrous alloys»

open access: yesЛитьë и металлургия, 2018
The information is given about the history of the Department of «Metallurgy of ferrous and non-ferrous alloys», which has undergone three changes in the name:» Foundry of ferrous and non – ferrous metals « – «Metallurgy of casting alloys» – «Metallurgy ...
B. M. Nemenenok, I. A. Trusova
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Legal education: challenges of the time and ways to overcome them

open access: yesИзвестия высших учебных заведений. Поволжский регион: Общественные науки
Background. Modern Russian legal education is at a turning point. In this regard, the choice of further ways of its development is of great importance, which determines the relevance of the research topic.
V.V. Goshulyak
doaj   +1 more source

CURRENT DIRECTIONS OF RESEARCH IN INFORMATION- COMMUNICATION TECHNOLOGIES IN THE FIELD OF PEDAGOGICAL SCIENCE.

open access: yesÌнформаційні технології в освіті, 2010
In the publication modern research areas of information-communication technologies in pedagogical science are identified. The basic requirements of the new passport for the specialty 13.00.10 - Information and Communication Technologies in Education are ...
O.N. Spirin, A.V. Svietlorusova
doaj  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

TECHNOLOGY OF IDENTIFYING EDUCATIONAL LEVELS ACCORDANCE AS INNOVATIVE APPROACH IN EDUCATIONAL SYSTEM

open access: yesÌнформаційні технології в освіті, 2015
The problem of raising the quality level of education determines the achieving new qualification levels of applicant for education. Universities, colleges, schools are interested in improving transition between qualification levels. The desire to improve
T. Filatova
doaj  

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