Results 131 to 140 of about 15,558,174 (350)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Water diviners described: six new species of the Niphargus aquilex (Crustacea, Amphipoda) complex

open access: yesEuropean Journal of Taxonomy
With the onset of molecular taxonomy, it has been recognized that groundwater crustaceans in the family Niphargidae Bousfield, 1977 (Crustacea, Amphipoda) can demonstrate either highly variable or static phenotypes.
Dieter Weber   +2 more
doaj   +1 more source

Voltammetric investigation of the complexation equilibria in the presence of a low level of supporting electrolyte Part 1: Steady-state current-potential curves for inert complexes [PDF]

open access: yes, 1997
The use of microelectrodes for voltammetric investigations of the complexation equilibria at very low concentrations of supporting electrolyte allows the risk of competitive complexation or contamination to be avoided, makes the activities of the species
Bos, M.   +4 more
core   +4 more sources

Comparative “Omics” of the Fusarium fujikuroi Species Complex Highlights Differences in Genetic Potential and Metabolite Synthesis

open access: yesGenome Biology and Evolution, 2016
Species of the Fusarium fujikuroi species complex (FFC) cause a wide spectrum of often devastating diseases on diverse agricultural crops, including coffee, fig, mango, maize, rice, and sugarcane.
Eva-Maria Niehaus   +25 more
semanticscholar   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The faunistic diversity of cave-dwelling spiders (Arachnida, Araneae) of Greece [PDF]

open access: yes, 2011
Until today, from Greek caves a total of 109 species of spiders belonging to 25 families are known. One species, the linyphiid Porrhomma convexum (Westring, 1861) was recorded here for the first time in Greece. The 109 species are distributed in caves of
Deltshev, Christo
core   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Preliminary genetic evidence of two different populations of Opisthorchis viverrini in Lao PDR [PDF]

open access: yes, 2017
Opisthorchis viverrini is a major public health concern in Southeast Asia. Various reports have suggested that this parasite may represent a species complex, with genetic structure in the region perhaps being dictated by geographical factors and ...
B Sripa   +48 more
core   +3 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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