Disrupting CSPG‐Driven Microglia–Astrocyte Crosstalk Enables Scar‐Free Repair in Spinal Cord Injury
This study identifies CSPGs as key drivers of glial scar maturation after spinal cord injury by reprogramming microglial metabolism and inducing astrocyte fibrosis. To address this, a reactive oxygen species‐responsive, reactive astrocyte‐targeted ChABC gene delivery system is designed to locally degrade CSPGs, precisely disrupt maladaptive glial ...
Yufei Zheng +10 more
wiley +1 more source
Deciphering Morphological Variability: Addressing Taxonomic Ambiguities in Contemporary Species Delimitation (Hymenoptera, Figitidae). [PDF]
Ferrer-Suay M +3 more
europepmc +1 more source
Species delimitation by DNA barcoding reveals undescribed diversity in Stelliferinae (Sciaenidae). [PDF]
da Silva TF +6 more
europepmc +1 more source
A phylogenetic approach to species delimitation in freshwater Gastrotricha from Sweden
Tobias Kånneby +2 more
openalex +2 more sources
Nanoparticle Immunoadjuvant Complexes Augment Germinal Center Responses to Vaccination
Scaffolding IL‐21 on the surface of a self‐assembling nanoparticle immunogen drives improved germinal center and humoral immune responses. These nanoparticle immunoadjuvant complexes (NICs) functionally modulate the germinal center driving improved somatic hypermutation and antibody maturation, suggesting this platform has potential utility as a ...
Nicholas J. Tursi +21 more
wiley +1 more source
Genomic Insights Into Species Delimitation and the Evolutionary History of Mimetic <i>Aletis</i> Moths (Lepidoptera, Geometridae) in the Afrotropics. [PDF]
Lee KM +9 more
europepmc +1 more source
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv +6 more
wiley +1 more source
Revisiting the Species Delimitation Within <i>Amolops mantzorum</i> (David, 1872), with a Description of a New Subspecies (Anura, Ranidae). [PDF]
Qian T +8 more
europepmc +1 more source
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu +13 more
wiley +1 more source

