Results 161 to 170 of about 1,799,458 (303)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Genus <i>Varma</i> (Hemiptera, Tropiduchidae): new species description and updated male and female identification keys. [PDF]

Zookeys
Zhou H, He L, Chen XS, Chang ZM.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

A new filarial nematode, <i>Litomosa vetuni</i> Pikula, Bednarikova & Řehulková n. sp. (Nematoda: Onchocercidae), from the parti-coloured bat <i>Vespertilio murinus</i> in Europe: An integrative species description. [PDF]

Curr Res Parasitol Vector Borne Dis
Řehulková E, Pikula J, Bednarikova S, Danek O, Mašová Š, Nemcova M, Piacek V, Zukalova K, Zukal J.   +8 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Integrative taxonomy and phylogenetic analyses of two <i>Ceratomyxa</i> species (Myxozoa, Ceratomyxidae) from the China Sea, including a new species description. [PDF]

Zookeys
Yang C, Yang Y, Chen X, Yang S, Zhou Y, Ma H, Liu Y, Zhao Y.   +7 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Global Geographical Patterns on the Historical Species Description Process of Fig Wasps (Agaonidae). [PDF]

Zool Stud
Hernández-Aguiar X, Rodríguez A, Nieves-Aldrey JL, Polidori C, Gómez JF, Gil-Tapetado D.   +5 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

<i>'Candidatus</i> Phytoplasma vignae', assigning a species description to a long-known phytoplasma occurring in northern Australia. [PDF]

Int J Syst Evol Microbiol
Rodrigues Jardim B, Tran-Nguyen LTT, Gambley C, Webster C, Kehoe M, Bond S, Rodoni B, Constable FE.   +7 more
europepmc   +1 more source