Results 41 to 50 of about 10,378,615 (244)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
PLoS ONE, 2016 Species distribution modeling has been widely used in studying habitat relationships and for conservation purposes. However, neglecting ecological knowledge about species, e.g.
Nima Madani +4 more
doaj +1 more source
Ecological Processes, 2021 Background As global temperatures continue to rise, species distribution modeling is a suitable tool for identifying rare and endangered species most at risk of extinction, along with tracking shifting geographical range.
Debasruti Boral, Saurav Moktan
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Espacio y Desarrollo, 2015 Species distribution modeling is presented as an analytical tool for biogeography and the study of climate change impact on biodiversity. Key modeling concepts and applications are reviewed; the maximum entropy principle is described as well as its ...
Martín Timaná de la Flor +1 more
doaj +1 more source
New locality records and geographic distribution map of Dendropsophus meridensis (Rivero, 1961) (Anura: Hylidae) in the Andes of Venezuela [PDF]
Check List, 2015 Dendropsophus meridensis is a medium-sized treefrog endemic to the Cordillera de Mérida in the Venezuelan Andes. The geographic distribution of this species is poorly known, and only 10 localities known in the literature.
Luis Armesto +2 more
doaj +3 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The influence of spatial errors in species occurrence data on distribution models
, 2008 1. Species distribution modelling is used increasingly in both applied and theoretical research to predict how species are distributed and to understand attributes of species' environmental requirements.
Scachetti Pereira, Ricardo +41 more
core +1 more source