Results 101 to 110 of about 2,034,414 (310)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Guiding conservation strategies for China’s Corybas species through species distribution modeling
Global Ecology and ConservationCorybas Salisb. is a widespread plant genus in the family Orchidaceae, known for its small, beautiful flowers. Most species in this genus are narrow endemics.
Li-Dan Tao +5 more
doaj +1 more source
A New Species of Coralliidae (Cnidaria: Octocorallia) Collected from Eastern Japan
Species Diversity, 2023 A new species of Hemicorallium Gray, 1867 (Coralliidae), Hemicorallium meraboshi sp. nov., is described here. The specimen was found at a depth of 1744–1755 m, approximately 340 km east of the Honshu (mainland Japan) coast.
Masanori Nonaka +2 more
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Description of a New Genus of Candimboididae (Polycladida: Acotylea) from the Coast of Sagami Bay
Species Diversity, 2023 We establish a new genus of candimboidid polyclad, Chimaeriplana gen. nov., based on a new species, C. japonica sp. nov., collected from Kanagawa, the coast of Sagami Bay, Japan. Chimaeriplana japonica sp. nov.
Yuki Oya, Morio Hagiya
doaj +1 more source
Protein O‐glycosylation in the Bacteroidota phylum
FEBS Open Bio, EarlyView.Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi +5 more
wiley +1 more source
Plastome phylogenomics, biogeography, and clade diversification of Paris (Melanthiaceae)
BMC Plant Biology, 2019 Background Paris (Melanthiaceae) is an economically important but taxonomically difficult genus, which is unique in angiosperms because some species have extremely large nuclear genomes.
Yunheng Ji +7 more
doaj +1 more source