Results 101 to 110 of about 2,078,364 (357)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Soil Microbial Networks Shift Across a High-Elevation Successional Gradient. [PDF]

, 2019
While it is well established that microbial composition and diversity shift along environmental gradients, how interactions among microbes change is poorly understood.
Bueno de Mesquita, Clifton P, Farrer, Emily C, King, Andrew J, Porazinska, Dorota L, Sartwell, Samuel A, Schmidt, Steven K, Smith, Jane G, Spasojevic, Marko J, Suding, Katharine N, White, Caitlin T   +9 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Species diversity in Pseudocercospora.

Fungal Syst Evol
Species of Pseudocercospora are commonly associated with leaf and fruit spots on diverse plant hosts in sub-tropical and tropical regions. Pseudocercospora spp. have mycosphaerella-like sexual morphs, but represent a distinct genus in Mycosphaerellaceae (Mycosphaerellales, Dothideomycetes).
Groenewald JZ, Chen YY, Zhang Y, Roux J, Shin HD, Shivas RG, Summerell BA, Braun U, Alfenas AC, Ujat AH, Nakashima C, Crous PW.   +11 more
europepmc   +5 more sources

Tree species effect on natural control of H. albipunctella de Joannis in a millet agroforestry system in Senegal [PDF]

, 2019
Association of several tree species in and around a plot can have a positive impact on ecosystem services. Thus, traditional agroforestry systems, characterized by a high plant diversity, constitute an ideal model of study to test if the natural tree ...
Brévault, Thierry, Diakhate, Mouhamadou, Soti, Valérie, Sow, Ahmadou, Thiaw, Ibrahima   +4 more
core  

Does functional soil microbial diversity contribute to explain within-site plant beta-diversity in an alpine grassland and a dehesa meadow in Spain? [PDF]

, 2017
Questions: Once that the effects of hydrological and chemical soil properties have been accounted for, does soil microbial diversity contribute to explain change in plant community structure (i.e. within-site beta-diversity)?
Araya, Yoseph N., Bartelheimer, Maik, Crujeiras, Rosa M., García-Baquero, Gonzalo, Valle, Cipriano J.   +4 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Transcriptome data analysis provides insights into the conservation of Michelia lacei, a plant species with extremely small populations distributed in Yunnan province, China

BMC Plant Biology
Background Michelia lacei W.W.Smith (Magnoliaceae), was classified as a Plant Species with Extremely Small Populations (PSESP) by the Yunnan Provincial Government in both action plans of 2012 and 2021. This evergreen tree is known for its high ornamental
Yang Liu, Lei Cai, Weibang Sun
doaj   +1 more source

Plant Species Diversity in Relation to Carbon Stocks at Jangkok Watershed, Lombok Island [PDF]

, 2013
The area around Jangkok watershed has changed, dividing it into some land use systems. This research aimed to study the effect of plant species diversity onC-stocks, and to analyse the characteristics of land use systems based on their similarity.
Hairiah, K. (Kurniatun), Markum, M. (Markum), Soesilaningsih, E. A. (Endang), Suprayogo, D. (Didik)   +3 more
core  

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source