Results 131 to 140 of about 2,660,707 (313)

Evaluation of the MeltPro Myco Assay for the Identification of Non-Tuberculous Mycobacteria

open access: yesInfection and Drug Resistance, 2022
Jian Lin,1,2 Yong Zhao,1,2 Shuzhen Wei,1,2 Zhisong Dai,1,2 Shufang Lin1,2 1Institute of Tuberculosis Control and Prevention, Fujian Center for Disease Control and Prevention, Fuzhou, People’s Republic of China; 2Fujian Provincial Key Laboratory of ...
Lin J, Zhao Y, Wei S, Dai Z, Lin S
doaj  

The American species of the annulatipes group of the subgenus Lepidohelea, genus Forcipomyia (Diptera: Ceratopogonidae) [PDF]

open access: yes, 2010
The annulatipes group of the genus Forcipomyia Meigen, subgenus Lepidohelea Kieffer, is represented in the Western Hemisphere by 12 species. Keys are presented for their identification, and to distinguish them from other groups of the subgenus ...
Spinelli, Gustavo R., Wirth, Willis W.
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Avabase: a taxonomic and epidemiological plateform resource for arthropods of interest for animal health [PDF]

open access: yes, 2012
Despite the general acknowledge that taxonomy is primordial, the decline in taxonomy and skills base for identifying and describing biodiversity is drastically declining.
Allene, Xavier   +9 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Keys to families of Cladocera and to subfamilies, genera, species and subspecies of Macrothricidae and Moinidae [Translation from: Leningrad, Fauna SSSR, Crustacea 1 (3), 1971] [PDF]

open access: yes, 1977
Identification keys to families of Cladocera and to subfamilies, genera, species and subspecies of Macrothricidae and Moinidae are given.
Smirnov, N.N.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Orthotrichum (Orthotrichaceae, Bryopsida) in Pakistan [PDF]

open access: yes, 2002
A first critical survey of the genus Orthotrichum in Pakistan is provided. The currently known geographical distributions of the species and their ecologies within Pakistan are discussed.
Gruber, Johann Peter   +1 more
core  

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