Results 71 to 80 of about 1,825,089 (356)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Checklist of Algerian fungi – Part 3: Laboulbeniales (Ascomycota) [PDF]
Microbial Biosystems Journal, 2019 Our third contribution to the checklist of Algerian fungi is dedicated to Labouls (Laboulbeniales, Laboulbeniomycetes) an a typical and very diversified group of microscopic fungi that unsure their nutrition and/or dispersal by being insect ectoparasites.
Said Amrani, Ahmed Abdel-Azeem
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Checklist of Algerian fungi – Part 2: Chromistan Fungal Analogues (Oomycota, Bigyra, Cercozoa) [PDF]
Microbial Biosystems Journal, 2018 This publication provides an updated checklist of Chromistan Fungal Analogues (CFA) in Algeria. This is a compilation of information on substrate and locality from where CFA fungi have been recorded. or original descriptions available.
doaj +1 more source
Spiders (Araneae) of Chernivtsi City (Ukraine) [PDF]
, 2012 The spider fauna of buildings and other urban habitats (city parks, green areas of industrial enterprises, and housing estates) of Chernivtsi city was surveyed. In the period 2002-2011, 212 species belonging to 26 families were recorded. Previous studies
Fedoriak, Mariia +3 more
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
An Annotated List of the Cerambycidae of Michigan (Coleoptera) Part II, the Subfamilies Lepturinae and Lamiinae [PDF]
, 2017 (excerpt) This is a continuation of Part I of an annotated list of the Cerambycidae known from Michigan, and includes the remaining subfamilies Lepturinae and Lamiinae. The format is similar to that used in Part I. We have largely followed the systematic
Gosling, D.C. L, Gosling, N. M
core +2 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Frogs of the Makuleke Contractual Park, northern Kruger National Park
Koedoe: African Protected Area Conservation and ScienceThe Kruger National Park is the largest protected area in South Africa and one of the most extensively surveyed in sub-Saharan Africa. Scientific studies, passive sampling from rangers and citizen science records have resulted in comprehensive faunal ...
Chad Keates +6 more
doaj +1 more source