Results 71 to 80 of about 233,597 (315)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Impact scores of invasive plants are biased by disregard of environmental co-variation and non-linearity [PDF]
, 2011 Prioritisation of high-impact species is becoming increasingly important for management of introduced species (‘neobiota’) because of their growing number of which, however, only a small fraction has substantial impacts.
Jan Thiele +12 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Attenuation of species abundance distributions by sampling [PDF]
, 2015 Quantifying biodiversity aspects such as species presence/ absence, richness and abundance is an important challenge to answer scientific and resource management questions.
Shimadzu, Hideyasu +3 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Global Ecology and ConservationThe ongoing loss of species diversity highlights necessitates elucidating the drivers of species richness to inform biodiversity conservation and sustainable forest management strategies.
Jianfeng Li +4 more
doaj +1 more source
Natura Sloveniae, 2018 Changes in butterfly fauna in the Koroška region in northeastern Slovenia have been compared over a period of 22 years. Records from 12 sampling sites from late July 2016 are compared with the same sites from late July/early August 1994. On average, 30%
Vid Švara, Rudi Verovnik
doaj +1 more source
Experimental Manipulation of Grassland Plant Diversity Induces Complex Shifts in Aboveground Arthropod Diversity. [PDF]
PLoS ONE, 2016 Changes in producer diversity cause multiple changes in consumer communities through various mechanisms. However, past analyses investigating the relationship between plant diversity and arthropod consumers focused only on few aspects of arthropod ...
Lionel R Hertzog +3 more
doaj +1 more source
, 2010 The New Zealand fish fauna contains species that are affected not only by river system connectivity, but also by catchment and local-scale changes in landcover, water quality and habitat quality.
McArthur, Kate +17 more
core +1 more source