Results 111 to 120 of about 1,253,213 (355)

Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients. [PDF]

, 2015
Quantification of disease-associated proteins in the cerebrospinal fluid (CSF) has been critical for the study and treatment of several neurodegenerative disorders; however, mutant huntingtin protein (mHTT), the cause of Huntington's disease (HD), is at ...
Andreas Weiss, Benjamini, Blair R. Leavitt, Douglas Langbehn, Douglas Macdonald, Edward J. Wild, Henrik Zetterberg, James R.C. Miller, Jeromin, Ko, Lewczuk, Nicola Robertson, Rainer Kuhn, Roberto Boggio, Rosengren, Salman Haider, Sarah J. Tabrizi   +16 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Comparative Pathogenicity and Host Ranges of Magnaporthe oryzae and Related Species

The Plant Pathology Journal, 2020
Host shifting and host expansion of fungal plant pathogens increases the rate of emergence of new pathogens and the incidence of disease in various crops, which threaten global food security. Magnaporthe species cause serious disease in rice, namely rice
doaj   +1 more source

Specificity of lipid transfer protein for molecular species of cholesteryl ester.

Journal of Lipid Research, 1988
The capacity of the plasma-derived lipid transfer protein to facilitate the transfer of various cholesteryl ester species has been investigated. Four different molecular species of cholesteryl ester were incorporated into either reconstituted high ...
R E Morton
doaj   +1 more source

Aggregation in an heterospecific population of blowfly larvae: social behaviour is impacted by species-specific thermal requirements and settlement order [PDF]

, 2023
Damien Charabidzé, Cindy Aubernon
openalex   +1 more source

Trematodes of the Great Barrier Reef, Australia: emerging patterns of diversity and richness in coral reef fishes [PDF]

, 2014
The Great Barrier Reef holds the richest array of marine life found anywhere in Australia, including a diverse and fascinating parasite fauna. Members of one group, the trematodes, occur as sexually mature adult worms in almost all Great Barrier Reef ...
Allen, Angel, Appeltans, Bott, Bott, Bott, Bott, Bott, Bray, Bray, Bray, Bray, Bray, Bray, Bray, Bray, Bray, Burger, Campbell, Chambers, Costello, Cribb, Cribb, Cribb, Cribb, Cribb, Cribb, Cutmore, Cutmore, Dayrat, Diaz, Downie, Gu, Gunter, Hafeezullah, Hall, Hanson, Heiniger, Ho, Hoese, Hunter, Hunter, Hunter, Jabbar, Johnston, Jones, Jones, Justine, Justine, Kamiya, Kayal, Lester, Lewis, Lo, Lucas, Magurran, Manter, Marissa K.A. McNamara, Mathew J. Nolan, McNamara, McNamara, McNamara, McNamara, Miller, Miller, Miller, Miller, Miller, Miller, Munday, Nabout, Nadler, Nahhas, Nathan J. Bott, Nolan, Nolan, Nolan, Overstreet, Overstreet, Palm, Pearson, Perez-Ponce de Leon, Post, Poulin, Poulin, Randall, Roberts-Thomson, Robertson, Rodney A. Bray, Rohde, Rohde, Rohner, Saoud, Scott C. Cutmore, Searle, Strona, Sun, Terrence L. Miller, Thomas H. Cribb, van Oppen, Whittington, Witenberg, Yamaguti, Yong   +103 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Sequence similarity is more relevant than species specificity in probabilistic backtranslation

BMC Bioinformatics, 2007
Background Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module.
Di Pietro Cinzia, Pulvirenti Alfredo, Pigola Giuseppe, Giugno Rosalba, Ferro Alfredo, Purrello Michele, Ragusa Marco   +6 more
doaj   +1 more source

A Lactobacillus helveticus -Specific DNA Probe Detects Restriction Fragment Length Polymorphisms in This Species [PDF]

, 1992
Clara G. de los Reyes‐Gavilán, G. K. Y. Limsowtin, Patrick Tailliez, Laurent Séchaud, Jean-Pierre Accolas   +4 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source