Results 141 to 150 of about 7,978 (300)
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
What Does It Mean to be Human, and Not Animal? Examining Montaigne’s Literary Persuasiveness in “Man is No Better Than the Animals” [PDF]
, 2018 Michel de Montaigne famously argued in “Man is No Better Than the Animals” that humans and non-human animals cannot be dichotomized based on language or reasoning abilities, among other characteristics.
Collins, Rory
core
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
A coffee with Jacques Rancière beneath the Acropolis [PDF]
, 2017 We met Jacques Rancière on Saturday, May 27, 2017, at the School of Fine Arts shortly before his speech at the B-Fest 6 International Anti-Authoritarian Festival, organized by Babylonia Journal, with a central slogan “We are ungovernable”.
Ktenas, Yiannis +2 more
core
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Compte rendu critique du livre Voir son steak comme un animal mort, de Martin Gibert
BioéthiqueOnline, 2016 This critical review provides, first, a step-by-step synthesis of the arguments presented in each chapter of Martin Gibert’s bookVoir son steak comme un animal mort (Seeing your steak as a dead animal).
Drolet, Marie-Josée
doaj
Synthesis philosophica, 2000 Speciesism is a position in applied ethics which claims that particular beings as such(i.e. humans) deserve a special moral status. Contrary to this position, the criticism says that this attitude is heavily discriminatory, comparable to racism, sexism, etc.
openaire +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Classic Psychedelics and Human-Animal Relations. [PDF]
Int J Environ Res Public Health, 2022 Pöllänen E +3 more
europepmc +1 more source